{"result":[{"lastName":"Kornberg","clinicalFocus":[],"appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4308&type=small&showNoImage","displayName":"Roger Kornberg","firstName":"Roger","href":"http://med.stanford.edu/profiles/Roger_Kornberg","researchInterest":"We study the regulation of transcription, the first step in gene expression. The main lines of our work are 1) reconstitution of the process with more than 50 pure proteins and mechanistic analysis, 2) structure determination of the 50 protein complex at atomic resolution, and 3) studies of chromatin remodelling, required for transcription of the DNA template in living cells"},{"lastName":"McAdams","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Developmental Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor (Research),Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4403&type=small&showNoImage","displayName":"Harley McAdams","firstName":"Harley","href":"http://med.stanford.edu/profiles/Harley_McAdams","researchInterest":"Experimental and theoretical analysis and modeling of genetic regulatory circuits, particularly bacterial regulation and with emphasis on global regulation of Caulobacter crescentus. Bioinformatic analysis of bacterial genomes, of microarray expression patterns, and cross-species genomic analysis. Techniques: gene expression microarrays, fluorescent microscopy, electron microscopy, genetics, molecular biology"},{"lastName":"Honaker","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pediatrics"}],"primaryAppointment":"Postdoctoral Research fellow, Pediatrics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=19298&type=small&showNoImage","displayName":"Ryan Honaker","firstName":"Ryan","href":"http://med.stanford.edu/profiles/Ryan_Honaker","researchInterest":""},{"lastName":"Shapiro","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4316&type=small&showNoImage","displayName":"Lucy Shapiro","firstName":"Lucille","href":"http://med.stanford.edu/profiles/Lucille_Shapiro","researchInterest":"A basic question in developmental biology involves the mechanisms used to generate the three-dimensional organization of a cell from a one-dimensional genetic code. Our goal is to define these mechanisms using both molecular genetics and biochemistry."},{"lastName":"Wang","clinicalFocus":[],"appointments":[{"appointment":"Professor,Materials Science and Engineering - Materials Science Operations"},{"appointment":"Professor,Electrical Engineering - Solid State and Photonics Laboratory Operations"},{"appointment":"Member,Bio-X"},{"appointment":"Professor (By courtesy),Radiology"}],"primaryAppointment":"Professor,Materials Science and Engineering - Materials Science Operations","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8087&type=small&showNoImage","displayName":"Shan X. Wang","firstName":"Shan","href":"http://med.stanford.edu/profiles/Shan_Wang","researchInterest":"Dr. Wang is a Co-PI of the Stanford-led Center for Cancer Nanotechnology Excellence and Translation (CCNE-T).  His research interests lie in magnetic nanotechnologies in general and include magnetic biochips, in vitro diagnostics, magnetic nanoparticles, nano-patterning, spin electronic materials and sensors, magnetic inductive heads, as well as magnetic integrated inductors and transformers."},{"lastName":"Theriot","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Professor,Microbiology & Immunology"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4432&type=small&showNoImage","displayName":"Julie Theriot","firstName":"Julie","href":"http://med.stanford.edu/profiles/Julie_Theriot","researchInterest":"We study the interactions between infectious bacteria and the human host cell actin cytoskeleton. Listeria monocytogenes and Shigella flexneri are unrelated food-borne bacterial pathogens that share a common mechanism of invasion and actin-dependent intercellular spread in epithelial cells. Our studies fall into three broad areas: the biochemical basis of actin-based motility by these bacteria, the biophysical mechanism of force generation, and the evolutionary origin of pathogenesis."},{"lastName":"Jardetzky","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4190&type=small&showNoImage","displayName":"Oleg Jardetzky","firstName":"Oleg","href":"http://med.stanford.edu/profiles/Oleg_Jardetzky","researchInterest":"Structure, dynamics and function of proteins involved in transport and regulatory processes; high resolution nuclear magnetic resonance studies of conformational transitions and protein folding; study of the mechanism of action of the trp-repressor, ankyrin-domain proteins and the development of programs to calculate protein solution structure"},{"lastName":"Silies","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurobiology"}],"primaryAppointment":"Postdoctoral Research fellow, Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=15236&type=small&showNoImage","displayName":"Marion Silies","firstName":"Marion","href":"http://med.stanford.edu/profiles/Marion_Silies","researchInterest":""},{"lastName":"Ptacin","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9825&type=small&showNoImage","displayName":"Jerod Ptacin","firstName":"Jerod","href":"http://med.stanford.edu/profiles/Jerod_Ptacin","researchInterest":""},{"lastName":"Torres","clinicalFocus":[],"appointments":[{"appointment":"MS, Dean's Office"}],"primaryAppointment":"MS, Dean's Office","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=20431&type=small&showNoImage","displayName":"Marisa Torres","firstName":"Marisa","href":"http://med.stanford.edu/profiles/Marisa_Torres","researchInterest":"biodefense, pathogen, virulence, antibiotic resistance, detection, forensics"},{"lastName":"Ferreyra","clinicalFocus":[],"appointments":[{"appointment":"Ph.D., Microbiology & Immunology"},{"appointment":"SPCS Summer Res Pgm Staff,Continuing Studies and Summer Session - Stanford Pre-Collegiate Studies"},{"appointment":"Stanford Student Employee,Continuing Studies and Summer Session - Stanford Pre-Collegiate Studies"}],"primaryAppointment":"Ph.D., Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=19784&type=small&showNoImage","displayName":"Jessica Ferreyra","firstName":"Jessica","href":"http://med.stanford.edu/profiles/Jessica_Ferreyra","researchInterest":"Mechanisms used by Clostridium difficile to emerge in the intestine."},{"lastName":"Storek","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Microbiology & Immunology"}],"primaryAppointment":"Postdoctoral Research fellow, Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=34606&type=small&showNoImage","displayName":"Kelly Colvin Storek","firstName":"Kelly","href":"http://med.stanford.edu/profiles/Kelly_Storek","researchInterest":""},{"lastName":"Falkow","clinicalFocus":[],"appointments":[{"appointment":"Professor Emeritus,Microbiology & Immunology"},{"appointment":"Emeritus Faculty, Acad Council,Microbiology & Immunology"}],"primaryAppointment":"Professor Emeritus,Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4488&type=small&showNoImage","displayName":"Stanley Falkow","firstName":"Stanley","href":"http://med.stanford.edu/profiles/Stanley_Falkow","researchInterest":"Dr. Falkow is no longer taking students or postdoctoral fellows in his laboratory.  \r\n\r\nPlease contact either Denise Monack (dmonack@stanford.edu) or Manuel Amieva (amieva@stanford.edu)."},{"lastName":"Moerner","clinicalFocus":[],"appointments":[{"appointment":"Member,Bio-X"}],"primaryAppointment":"Member,Bio-X","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8121&type=small&showNoImage","displayName":"W. E. Moerner","firstName":"W","href":"http://med.stanford.edu/profiles/W_Moerner","researchInterest":"Physical chemistry/chemical physics: single-molecule imaging and spectroscopy in condensed phases; superresolution imaging of biomolecules in cells; fluorophores for cellular imaging; single-molecule biophysics; nanophotonics to produce enhanced optical fields; trapping single molecules in solution"},{"lastName":"Monack","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Microbiology & Immunology"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Associate Professor,Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8324&type=small&showNoImage","displayName":"Denise M. Monack","firstName":"Denise","href":"http://med.stanford.edu/profiles/Denise_Monack","researchInterest":"The primary focus of my research is to understand the genetic and molecular mechanisms of intracellular bacterial pathogenesis.  We use two model systems, Salmonella typhimurium and Francisella tularensis, to study the complex host-pathogen interactions.  Ultimately we would like to understand how Salmonella persists within certain hosts for years in the face of a robust immune response and how F. tularensis, a stealth invader, can cause a rapid, lethal infection."},{"lastName":"Elmlund","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Structural Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=23183&type=small&showNoImage","displayName":"Dominika Elmlund","firstName":"Dominika","href":"http://med.stanford.edu/profiles/Dominika_Elmlund","researchInterest":"I am interested in the structural biology of TFIID-dependent transcription. My investigations are focused toward determining the roles of TBP-lacking and TBP-containing TFIID states in the dynamic transcription initiation process. I am also involved in development of new computational methods for 3D structure determination from electron microscopic projection images of single-particles. The collection of algorithms developed so far constitutes a new open source software package SIMPLE (Single-p"},{"lastName":"Yanofsky","clinicalFocus":[],"appointments":[{"appointment":"Professor Emeritus,Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Professor Emeritus,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6252&type=small&showNoImage","displayName":"Charles Yanofsky","firstName":"Charles","href":"http://med.stanford.edu/profiles/Charles_Yanofsky","researchInterest":""},{"lastName":"Amieva","clinicalFocus":[{"focus":"Infectious Diseases, Pediatric"},{"focus":"Pediatric Infectious Disease"}],"appointments":[{"appointment":"Associate Professor,Pediatrics - Infectious Diseases"},{"appointment":"Associate Professor,Microbiology & Immunology"}],"primaryAppointment":"Associate Professor,Pediatrics - Infectious Diseases","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6150&type=small&showNoImage","displayName":"Manuel Amieva","firstName":"Manuel","href":"http://med.stanford.edu/profiles/Manuel_Amieva","researchInterest":"My laboratory studies the strategies pathogens utilize to colonize and subvert the epithelial barrier. We have focused on the epithelial junctions as a target for bacterial pathogens, since the cell-cell junctions serve as both a barrier to infection and also a major control site for epithelial function. In particular, we are interested in how the gastric pathogen Helicobater pylori may cause cancer by interfering with cell signaling at the epithelial junctions.  We are also studying how variou"},{"lastName":"Huang","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Bioengineering"},{"appointment":"Assistant Professor,Microbiology & Immunology"}],"primaryAppointment":"Assistant Professor,Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10429&type=small&showNoImage","displayName":"KC Huang","firstName":"Kerwyn","href":"http://med.stanford.edu/profiles/Kerwyn_Huang","researchInterest":""}]}