{"result":[{"lastName":"Steinman","clinicalFocus":[{"focus":"Neurology"},{"focus":"Neurology, Pediatric"},{"focus":"Multiple Sclerosis, Myasthenia Gravis, Immune Disorders"}],"appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Member,Bio-X"},{"appointment":"Professor,Pediatrics"}],"primaryAppointment":"Professor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3784&type=small&showNoImage","displayName":"Lawrence Steinman","firstName":"Lawrence","href":"http://med.stanford.edu/profiles/Lawrence_Steinman","researchInterest":"Our laboratory is dedicated to understanding the pathogenesis of autoimmune diseases, particularly multiple sclerosis.  We have developed several new therapies for autoimmunity, including some in Phase 2 clinical trials, as well as one approved drug, natalizumab.  We have developed microarray technology for detecting autoantibodies to myelin proteins and lipids.  We employ a diverse range of molecular and celluar approaches to trying to understand multiple sclerosis."},{"lastName":"Robinson","clinicalFocus":[{"focus":"Immunology and Rheumatology"},{"focus":"Rheumatology"}],"appointments":[{"appointment":"Associate Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4730&type=small&showNoImage","displayName":"William Robinson","firstName":"William","href":"http://med.stanford.edu/profiles/William_Robinson","researchInterest":"Our lab studies the molecular mechanisms of and develops therapies to treat autoimmune and rheumatic diseases, with a focus on rheumatoid arthritis, multiple sclerosis, and osteoarthritis. \r\n\r\nThe overriding objectives of our laboratory are:\r\n\r\n1. To investigate the mechanisms underlying autoimmune diseases.\r\n\r\n2. To develop diagnostics and therapeutics for autoimmune diseases.\r\n\r\n3. To investigate the role of inflammation in osteoarthritis."},{"lastName":"Sobel","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4269&type=small&showNoImage","displayName":"Raymond A. Sobel, M.D.","firstName":"Raymond","href":"http://med.stanford.edu/profiles/Raymond_Sobel","researchInterest":"We study cellular and molecular mechanisms of immune-mediated injury in central nervous system (CNS) tissues  that are altered in multiple sclerosis (MS). Tissues of patients and of animals with experimental allergic encephalomyelitis are analyzed using histology and immunohistochemistry.  We currently are studying the cross-recognition of neurons by antibodies against myelin proteolipid protein epitopes.  Similar cross-recognition may link anti-myelin immunity with neurodegeneration in MS."},{"lastName":"Ko","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10414&type=small&showNoImage","displayName":"Rose Ko","firstName":"Rose","href":"http://med.stanford.edu/profiles/Rose_Ko","researchInterest":""},{"lastName":"Mellins","clinicalFocus":[],"appointments":[{"appointment":"Professor - Med Center Line,Pediatrics - Human Gene Therapy"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Professor - Med Center Line,Pediatrics - Human Gene Therapy","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5952&type=small&showNoImage","displayName":"Elizabeth Mellins","firstName":"Elizabeth","href":"http://med.stanford.edu/profiles/Elizabeth_Mellins","researchInterest":"Molecular mechanisms and intracellular pathways of antigen processing and presentation; structure/function of HLA-DR,-DM, -DO; HLA allele association with disease; disease mechanisms in systemic idiopathic juveile arthritis"},{"lastName":"Cho","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pathology"}],"primaryAppointment":"Postdoctoral Research fellow, Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=13052&type=small&showNoImage","displayName":"Ah Ryon Cho","firstName":"Ah Ryon","href":"http://med.stanford.edu/profiles/Ah Ryon_Cho","researchInterest":""},{"lastName":"Lane","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty-Med Ctr Line,Radiology"}],"primaryAppointment":"Emeritus Faculty-Med Ctr Line,Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4172&type=small&showNoImage","displayName":"Barton Lane","firstName":"Barton","href":"http://med.stanford.edu/profiles/Barton_Lane","researchInterest":"As a professor in the Medical Center Line, my primary investigative interest has been in clinical neuroradiology. This encompasses spinal cord and spine disease, degenerative and demyelinating diseases of the central nervous system, strokes and infarction, and chronic epilepsy syndromes. Facial and head and neck vascular malformations and hemangiomas have been a focus of interest for many years, with collaborative projects involving dermatology and functional restoration services."},{"lastName":"Smith","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Neurology & Neurological Sciences"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7015&type=small&showNoImage","displayName":"Marion Smith","firstName":"Marion","href":"http://med.stanford.edu/profiles/Marion_Smith","researchInterest":""},{"lastName":"Weyand","clinicalFocus":[{"focus":"Immunology"},{"focus":"Vasculitis"},{"focus":"Rheumatoid Arthritis"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=15618&type=small&showNoImage","displayName":"Cornelia Weyand","firstName":"Cornelia","href":"http://med.stanford.edu/profiles/Cornelia_Weyand","researchInterest":""},{"lastName":"Genovese","clinicalFocus":[{"focus":"Rheumatology"},{"focus":"Immunology/Rheumatology"}],"appointments":[{"appointment":"Professor - Med Center Line,Medicine - Immunology & Rheumatology"}],"primaryAppointment":"Professor - Med Center Line,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4195&type=small&showNoImage","displayName":"Mark Genovese","firstName":"Mark","href":"http://med.stanford.edu/profiles/Mark_Genovese","researchInterest":"Clinical trials and interventions in the rheumatic diseases including Rheumatoid Arthritis,Systemic Lupus Erythematosus, Systemic Sclerosis, Osteoarthritis."},{"lastName":"Goronzy","clinicalFocus":[{"focus":"Vasculitis"},{"focus":"Rheumatoid Arthritis"},{"focus":"Immunology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=15394&type=small&showNoImage","displayName":"Jorg Goronzy","firstName":"Jorg","href":"http://med.stanford.edu/profiles/Jorg_Goronzy","researchInterest":""},{"lastName":"Nelson","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Health Research & Policy - Epidemiology"}],"primaryAppointment":"Associate Professor,Health Research & Policy - Epidemiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4277&type=small&showNoImage","displayName":"Lorene Nelson, PhD","firstName":"Lorene","href":"http://med.stanford.edu/profiles/Lorene_Nelson","researchInterest":"Primary research interests:  (1) genetic and environmental determinants of neurodegenerative disorders, including Parkinson's disease, amyotrophic lateral sclerosis and multiple sclerosis, (2) genetic epidemiology and approaches for identifying gene-environment interactions, (3) genetic and environmental determinants of autoimmune disease."},{"lastName":"Simard","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Health Research & Policy - Epidemiology"},{"appointment":"Assistant Professor (By courtesy),Medicine - Immunology & Rheumatology"}],"primaryAppointment":"Assistant Professor,Health Research & Policy - Epidemiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=35300&type=small&showNoImage","displayName":"Julia Simard","firstName":"Julia","href":"http://med.stanford.edu/profiles/Julia_Simard","researchInterest":""},{"lastName":"Feng","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Molecular & Cellular Physiology"}],"primaryAppointment":"Assistant Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=35054&type=small&showNoImage","displayName":"Liang Feng","firstName":"Liang","href":"http://med.stanford.edu/profiles/Liang_Feng","researchInterest":"We are interested in the structure, dynamics and function of eukaryotic transport proteins mediating ions and major nutrients crossing the membrane, the kinetics and regulation of transport processes, the catalytic mechanism of membrane embedded enzymes and the development of small molecule modulators based on the structure and function of membrane proteins."},{"lastName":"Ajami","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences"}],"primaryAppointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=30648&type=small&showNoImage","displayName":"Bahareh Ajami","firstName":"Bahareh","href":"http://med.stanford.edu/profiles/Bahareh_Ajami","researchInterest":""},{"lastName":"Varr","clinicalFocus":[{"focus":"Internal Medicine"}],"appointments":[{"appointment":"Clinical Instructor,Medicine - General Medical Disciplines"}],"primaryAppointment":"Clinical Instructor,Medicine - General Medical Disciplines","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=35532&type=small&showNoImage","displayName":"Brandon Varr","firstName":"Brandon","href":"http://med.stanford.edu/profiles/Brandon_Varr","researchInterest":""},{"lastName":"Luo","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Neurology & Neurological Sciences"}],"primaryAppointment":"Instructor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9626&type=small&showNoImage","displayName":"Jian Luo","firstName":"Jian","href":"http://med.stanford.edu/profiles/Jian_Luo","researchInterest":"Relevance of cytokine-mediated neuro-immune crosstalk in neurodegenerative disease."},{"lastName":"Steinberg","clinicalFocus":[{"focus":"Cerebrovascular and Spinal Vascular Surgery"},{"focus":"Intracranial Aneurysms"},{"focus":"Intracranial/Intraspinal AVMs, AV fistulas, Cavernous Malformations"},{"focus":"Moyamoya Disease and Occlusive Cerebrovascular Disease"},{"focus":"Carotid Endarterectomy"},{"focus":"Neurosurgery"}],"appointments":[{"appointment":"Professor,Neurosurgery"},{"appointment":"Member,Bio-X"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Neurosurgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4646&type=small&showNoImage","displayName":"Gary K. Steinberg, MD, PhD","firstName":"Gary","href":"http://med.stanford.edu/profiles/Gary_Steinberg","researchInterest":"Our laboratory investigates the pathophysiology and treatment of acute cerebral ischemia, as well as methods to restore neurologic function after stroke. Treatment strategies include mild brain hypothermia, gene transfer therapy and stem cell transplantation. Our clinical research develops innovative surgical, endovascular and radiosurgical approaches for treating patients with difficult intracranial aneurysms, complex vascular malformations and occlusive disease, including Moyamoya disease."},{"lastName":"Dunn","clinicalFocus":[{"focus":"Multiple Sclerosis"},{"focus":"Neuromyelitis Optica"},{"focus":"Transverse Myelitis"},{"focus":"Neurology"}],"appointments":[{"appointment":"Clinical Professor,Neurology & Neurological Sciences"}],"primaryAppointment":"Clinical Professor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8456&type=small&showNoImage","displayName":"Jeffrey Dunn, MD","firstName":"Jeffrey","href":"http://med.stanford.edu/profiles/Jeffrey_Dunn","researchInterest":"Translational research in the human application of emerging immunotherapies for neurological disease, focusing on Multiple Sclerosis, CIS, transverse myelitis and Neuromyelitis Optica (NMO). Collaborative research with Stanford and extramural scientific faculty to identify biomarkers of disease activity and treatment response in humans. Clinical trials to assess efficacy of emerging treatments for MS, CIS and NMO, recently including trials of alemtuzumab, oral sphingosine 1 phosphate inhibition"},{"lastName":"VanHaren","clinicalFocus":[{"focus":"Leukodystrophies"},{"focus":"Autoimmune Diseases of the Nervous System"},{"focus":"Neurology - Child Neurology"}],"appointments":[{"appointment":"Instructor,Neurology & Neurological Sciences"}],"primaryAppointment":"Instructor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=18487&type=small&showNoImage","displayName":"Keith Van Haren","firstName":"Keith","href":"http://med.stanford.edu/profiles/Keith_VanHaren","researchInterest":"Our research is focused on the immune response in multiple sclerosis and X-linked adrenoleukodystrophy (ALD), with particular interest in the role of macrophages, lipids, and oxidative stress."},{"lastName":"Wyss-Coray","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Professor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3929&type=small&showNoImage","displayName":"Tony Wyss-Coray","firstName":"Tony","href":"http://med.stanford.edu/profiles/Tony_Wyss-Coray","researchInterest":"Use of genetic and molecular tools to dissect immune and inflammatory pathways in Alzheimer's and neurodegeneration."},{"lastName":"Krishnan","clinicalFocus":[{"focus":"Immunology and Rheumatology"},{"focus":"Rheumatology"},{"focus":"Gout"},{"focus":"Lupus"},{"focus":"arthritis"}],"appointments":[{"appointment":"Assistant Professor,Medicine - Immunology & Rheumatology"}],"primaryAppointment":"Assistant Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8452&type=small&showNoImage","displayName":"Eswar Krishnan, MD M.Phil","firstName":"Eswar","href":"http://med.stanford.edu/profiles/Eswar_Krishnan","researchInterest":"I am a clinical epidemiologist. My long-term goal is to develop ways and means of disease prevention in the context of rheumatic diseases. Currently, my core  investigative areas are: 1) Cardiovascular impact of inflammatory arthritis 2) Healthcare utilization of populations 3) Methodological innovations for improvement of individual and population phenotyping and health outcome measurement 4)Health outcomes in extreme old age."}]}