{"result":[{"lastName":"Voskoboynik","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Pathology - Stem Cell Institute"}],"primaryAppointment":"Instructor,Pathology - Stem Cell Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=17299&type=small&showNoImage","displayName":"Ayelet Voskoboynik","firstName":"Ayelet","href":"http://med.stanford.edu/profiles/Ayelet_Voskoboynik","researchInterest":"We study several stem cell interrelated phenomena using the protochordate, Botryllus schlosseri. We use genetic, genomic, and cell biological approaches to investigate: The evolutionary molecular mechanisms that regulate the decline of tissue regenerative potential during aging and allogeneic stem cell competition in host."},{"lastName":"Weissman","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology - Stem Cell Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor (By courtesy),Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Professor,Pathology - Stem Cell Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4605&type=small&showNoImage","displayName":"Irving Weissman","firstName":"Irving","href":"http://med.stanford.edu/profiles/Irving_Weissman","researchInterest":"Stem cell and cancer stem cell biology; development of T and B lymphocytes; cell-surface receptors for oncornaviruses in leukemia. Hematopoietic stem cells; Lymphocyte homing, lymphoma invasiveness and metastasis."},{"lastName":"Webb","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9984&type=small&showNoImage","displayName":"Ashley Webb","firstName":"Ashley","href":"http://med.stanford.edu/profiles/Ashley_Webb","researchInterest":"Stem cell function requires both the establishment and maintenance of particular epigenetic states. Perturbation of the epigenetic status of stem cells may compromise both self-renewal and multipotency. Work from our lab has identified the Forkhead family transcription factor, FoxO3, as a regulator of adult neural stem cell (NSCs) quiescence, which prevents the depletion of this population of cells. Along with recent evidence that Forkhead family members act as \u0091pioneer factors\u0092 in the opening "},{"lastName":"Brett","clinicalFocus":[],"appointments":[{"appointment":"MD Student, School of Medicine"},{"appointment":"Ph.D., Stem Cell"}],"primaryAppointment":"MD Student, School of Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=18662&type=small&showNoImage","displayName":"Jamie Brett","firstName":"Jamie","href":"http://med.stanford.edu/profiles/Jamie_Brett","researchInterest":"Aging, stem cells, DNA methylation"},{"lastName":"Charville","clinicalFocus":[],"appointments":[{"appointment":"MD Student, School of Medicine"},{"appointment":"Ph.D., Developmental Biology"}],"primaryAppointment":"MD Student, School of Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=18057&type=small&showNoImage","displayName":"Gregory Charville","firstName":"Gregory","href":"http://med.stanford.edu/profiles/Gregory_Charville","researchInterest":""},{"lastName":"Morgan","clinicalFocus":[],"appointments":[{"appointment":"MD Student, School of Medicine"}],"primaryAppointment":"MD Student, School of Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=20071&type=small&showNoImage","displayName":"Alexander A. Morgan","firstName":"Alexander","href":"http://med.stanford.edu/profiles/Alexander_Morgan","researchInterest":""},{"lastName":"Seita","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Stem Cell - Stem Cell Biology and Regenerative Medicine Institute"}],"primaryAppointment":"Instructor,Stem Cell - Stem Cell Biology and Regenerative Medicine Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10040&type=small&showNoImage","displayName":"Jun Seita","firstName":"Jun","href":"http://med.stanford.edu/profiles/Jun_Seita","researchInterest":""},{"lastName":"Denko","clinicalFocus":[],"appointments":[{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Member,Stanford Cancer Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4577&type=small&showNoImage","displayName":"Nicholas Denko","firstName":"Nicholas","href":"http://med.stanford.edu/profiles/Nicholas_Denko","researchInterest":"We are interested in the biologic effect of gene expression changes that occur in the solid tumor.  Many of these expression changes are due to the micro-physiology within the tumor.  Several of these genes have been implicated in driving malignant progression and/or regulating response to therapeutic intervention.  We hope to use these molecular changes to develop novel targeted therapies that take advantage of tumor specific gene expression changes."},{"lastName":"Cooke","clinicalFocus":[{"focus":"Cardiovascular Disease"},{"focus":"Cardiovascular Medicine"}],"appointments":[{"appointment":"Professor,Medicine - Cardiovascular Medicine"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4115&type=small&showNoImage","displayName":"John Cooke, MD, PhD","firstName":"John","href":"http://med.stanford.edu/profiles/John_Cooke","researchInterest":"Our translational research program in vascular regeneration is focused on generating and characterizing vascular cells from human induced pluripotential stem cells. We are also studying the therapeutic application of these cells in murine models of peripheral arterial disease.   In these studies we leverage our longstanding interest in endothelial signaling, eg by nitric oxide synthase (NOS) as well as by  nicotinic cholinergic receptors (nAChR)."},{"lastName":"Ronaghi","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Otolaryngology (Head and Neck Surgery)"}],"primaryAppointment":"Postdoctoral Research fellow, Otolaryngology (Head and Neck Surgery)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=18186&type=small&showNoImage","displayName":"Mohammad Ronaghi","firstName":"Mohammad","href":"http://med.stanford.edu/profiles/Mohammad_Ronaghi","researchInterest":""},{"lastName":"Sidow","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Associate Professor,Genetics"}],"primaryAppointment":"Associate Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4393&type=small&showNoImage","displayName":"Arend Sidow","firstName":"Arend","href":"http://med.stanford.edu/profiles/Arend_Sidow","researchInterest":"We are interested in the systems biology of molecular phenotypes, and how genetic variation affects them. The lab combines experimental approaches in developing mouse embryos as well as human cancers with computational analyses. Our main data engine is high-throughput sequencing. Please refer to our web site for more information:  http://mendel.stanford.edu/SidowLab/index.html"},{"lastName":"Leeper","clinicalFocus":[{"focus":"Vascular Medicine"},{"focus":"Cardiovascular Medicine"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Surgery - Vascular Surgery"},{"appointment":"Assistant Professor - Med Center Line,Medicine - Cardiovascular Medicine"}],"primaryAppointment":"Assistant Professor - Med Center Line,Surgery - Vascular Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9669&type=small&showNoImage","displayName":"Nicholas Leeper","firstName":"Nicholas","href":"http://med.stanford.edu/profiles/Nicholas_Leeper","researchInterest":""},{"lastName":"Zhang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Stem Cell"}],"primaryAppointment":"Postdoctoral Research fellow, Stem Cell","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=20935&type=small&showNoImage","displayName":"Pengbo Zhang","firstName":"Pengbo","href":"http://med.stanford.edu/profiles/Pengbo_Zhang","researchInterest":""},{"lastName":"Mulyasasmita","clinicalFocus":[],"appointments":[{"appointment":"Ph.D., Bioengineering"}],"primaryAppointment":"Ph.D., Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=19579&type=small&showNoImage","displayName":"Widya Mulyasasmita","firstName":"Widya","href":"http://med.stanford.edu/profiles/Widya_Mulyasasmita","researchInterest":""},{"lastName":"Smeriglio","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Orthopaedic Surgery"}],"primaryAppointment":"Postdoctoral Research fellow, Orthopaedic Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=35186&type=small&showNoImage","displayName":"Piera Smeriglio","firstName":"Piera","href":"http://med.stanford.edu/profiles/Piera_Smeriglio","researchInterest":""},{"lastName":"Heilshorn","clinicalFocus":[],"appointments":[{"appointment":"Member,Bio-X"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Member,Bio-X","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8100&type=small&showNoImage","displayName":"Sarah Heilshorn","firstName":"Sarah","href":"http://med.stanford.edu/profiles/Sarah_Heilshorn","researchInterest":"Protein engineering\r\nTissue engineering\r\nRegenerative medicine\r\nBiomaterials"},{"lastName":"Palmer","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Neurosurgery"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Neurosurgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5930&type=small&showNoImage","displayName":"Theo Palmer","firstName":"Theo","href":"http://med.stanford.edu/profiles/Theo_Palmer","researchInterest":"For most areas of the mammalian brain, the production of new nerve cells or neurons is restricted to fetal development. However, there are exceptions to the rule. Some areas of the brain continue to make new neurons throughout life. This neurogenesis is mediated by neural stem cells and our research goals are to understand how stem cell activity and fate are controlled. Ultimately, we hope to harness the nascent potential of stem cells to treat neurological injury and disease."},{"lastName":"Kosinski","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=17415&type=small&showNoImage","displayName":"Cynthia Kosinski","firstName":"Cynthia","href":"http://med.stanford.edu/profiles/Cynthia_Kosinski","researchInterest":""},{"lastName":"Ge","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=21246&type=small&showNoImage","displayName":"Xuecai Ge","firstName":"Xuecai","href":"http://med.stanford.edu/profiles/Xuecai_Ge","researchInterest":"I am interested in how the Hedgehog signaling transduction is regulated, and how the mis-regulation of Hedgehog pathway leads to human diseases such as Medulloblastoma."},{"lastName":"Phadnis","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Stem Cell"}],"primaryAppointment":"Postdoctoral Research fellow, Stem Cell","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=17601&type=small&showNoImage","displayName":"Smruti Phadnis","firstName":"Smruti","href":"http://med.stanford.edu/profiles/Smruti_Phadnis","researchInterest":""},{"lastName":"Harel","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=37895&type=small&showNoImage","displayName":"Itamar Harel","firstName":"Itamar","href":"http://med.stanford.edu/profiles/Itamar_Harel","researchInterest":"The overarching goal of the Brunet lab is to understand the genetic mechanisms of aging and longevity. Aging is a highly plastic process regulated by a combination of genetic and environmental factors. \r\n\r\nI am interested in the basic molecular components that characterize \u0093young\u0094 and \u0093aged\u0094 cellular states. Aging is associated with an increased onset of cancer, and I seeks to define the set of factors that can rejuvenate an aged cell, without the risk of malignant transformation. Ultimately, w"},{"lastName":"Chen","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Assistant Professor,Microbiology & Immunology - Baxter Laboratory","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6384&type=small&showNoImage","displayName":"Chang-Zheng Chen","firstName":"Chang-Zheng","href":"http://med.stanford.edu/profiles/Chang-Zheng_Chen","researchInterest":"We study the genetic networks controlled by regulatory RNAs, such as microRNAs (miRNAs), and currently focus on two complementary aspects of miRNA biology: (1) The roles of miRNAs in modulating the development, function, and pathogenesis of vertebrate immune systems and (2) the mechanisms by which these regulatory RNAs control gene expression."},{"lastName":"Cleary","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Pediatrics"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4506&type=small&showNoImage","displayName":"Michael Cleary","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Cleary","researchInterest":"The role of oncoproteins in cancer and development; molecular and cellular biology of hematologic malignancies; targeted molecular therapies of cancer."}]}