{"result":[{"lastName":"Lu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Pathology"}],"primaryAppointment":"Associate Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3976&type=small&showNoImage","displayName":"Bingwei Lu","firstName":"Bingwei","href":"http://med.stanford.edu/profiles/Bingwei_Lu","researchInterest":"We are interested in understanding how neural stem cells balance their self-renewal and differentiation and how deregulation of this process can result in brain tumor. We are also interested in mechanisms of neurodegeneration in Alzheimer\u0092s and Parkinson\u0092s diseases. We are using both Drosophila and mammalian models to address these fundamental questions."},{"lastName":"Krasnow","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4120&type=small&showNoImage","displayName":"Mark Krasnow","firstName":"Mark","href":"http://med.stanford.edu/profiles/Mark_Krasnow","researchInterest":"-  Lung development and stem cells\r\n-  Neural control of breathing\r\n-  Lung diseases including lung cancer\r\n-  New genetic model organisms for medicine"},{"lastName":"Baker","clinicalFocus":[],"appointments":[{"appointment":"Professor Emeritus,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor Emeritus,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6206&type=small&showNoImage","displayName":"Bruce Baker","firstName":"Bruce","href":"http://med.stanford.edu/profiles/Bruce_Baker","researchInterest":""},{"lastName":"Mourrain","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Psychiatry & Behavioral Science - Sleep Center"}],"primaryAppointment":"Associate Professor (Research),Psychiatry & Behavioral Science - Sleep Center","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=24313&type=small&showNoImage","displayName":"Philippe Mourrain","firstName":"Philippe","href":"http://med.stanford.edu/profiles/Philippe_Mourrain","researchInterest":""},{"lastName":"Greenberg","clinicalFocus":[],"appointments":[{"appointment":"Professor,Medicine - Gastroenterology & Hepatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Professor,Microbiology & Immunology"}],"primaryAppointment":"Professor,Medicine - Gastroenterology & Hepatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3791&type=small&showNoImage","displayName":"Harry B Greenberg","firstName":"Harry","href":"http://med.stanford.edu/profiles/Harry_Greenberg","researchInterest":"Molecular mechanisms of pathogenesis; determinants of protective immunity; host range and tissue tropism in liver and GI tract pathogenic viruses and studies of vaccines in people."},{"lastName":"Bass","clinicalFocus":[{"focus":"Gastroenterology/Nutrition/Hepatology, Pediatric"},{"focus":"Pediatric Gastroenterology"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Pediatrics - Gastroenterology"}],"primaryAppointment":"Associate Professor - Med Center Line,Pediatrics - Gastroenterology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4017&type=small&showNoImage","displayName":"Dorsey Bass","firstName":"Dorsey","href":"http://med.stanford.edu/profiles/Dorsey_Bass","researchInterest":"Our laboratory is interested in the pathophysiology, immunology, and epidemiology of viral gastroenteritis."},{"lastName":"Pringle","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7022&type=small&showNoImage","displayName":"John R. Pringle","firstName":"John","href":"http://med.stanford.edu/profiles/John_Pringle","researchInterest":"Much of our research exploits the power of yeast as an experimentally tractable model eukaryote to investigate fundamental problems in cell and developmental biology such as the mechanisms of cell polarization and cytokinesis.  In another project, we are developing the small sea anemone Aiptasia as a model system for study of the molecular and cellular biology of dinoflagellate-cnidarian symbiosis, which is critical for the survival of most corals but still very poorly understood."},{"lastName":"Roelens","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=32818&type=small&showNoImage","displayName":"Baptiste Roelens","firstName":"Baptiste","href":"http://med.stanford.edu/profiles/Baptiste_Roelens","researchInterest":""},{"lastName":"Snyder","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=13465&type=small&showNoImage","displayName":"Michael Snyder","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Snyder","researchInterest":"We are presently in an omics revolution in which genomes and other omes can be readily characterized. Our laboratory uses a variety of approaches to analyze genomes and regulatory networks. Our research focuses on yeast, an ideal model organism ideally suited to genetic analysis, and humans.\r\n\r\n1) Transcriptomes\r\nTo annotate genomes, we developed RNA sequencing for annotation the yeast and human transcriptomes. We discovered that the eukaryotic transcriptome is much more complex than previously"},{"lastName":"Yang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Stem Cell"}],"primaryAppointment":"Postdoctoral Research fellow, Stem Cell","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=18228&type=small&showNoImage","displayName":"Nan Yang","firstName":"Nan","href":"http://med.stanford.edu/profiles/Nan_Yang","researchInterest":""},{"lastName":"Clandinin","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Neurobiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3885&type=small&showNoImage","displayName":"Thomas Clandinin","firstName":"Thomas","href":"http://med.stanford.edu/profiles/Thomas_Clandinin","researchInterest":"My lab addresses two distinct questions.  That is, how can precise patterns of neuronal connections be genetically programmed during development, and how, once formed, can such circuits be used to mediate complex visual behaviors?   Using the fruit fly visual system as a model, we employ genetic approaches to manipulate the functions of genes and neurons. From this, we infer specific developmental roles for particular molecules, and infer specific computational roles for individual neurons."},{"lastName":"Chen","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Chemical and Systems Biology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Associate Professor,Developmental Biology"},{"appointment":"Associate Professor (By courtesy),Natural Sciences Cluster - Chemistry Department"}],"primaryAppointment":"Associate Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3938&type=small&showNoImage","displayName":"James K. Chen","firstName":"James","href":"http://med.stanford.edu/profiles/James_Chen","researchInterest":"Our laboratory combines synthetic chemistry and developmental biology to investigate the molecular events that regulate embryonic patterning, tissue regeneration, and tumorigenesis.  We are currently using genetic and small-molecule approaches to study the molecular mechanisms of Hedgehog signaling, and we are developing chemical technologies to perturb and observe the genetic programs that underlie vertebrate development."},{"lastName":"Park","clinicalFocus":[],"appointments":[{"appointment":"Basic Life Science Research Associate,Developmental Biology"}],"primaryAppointment":"Basic Life Science Research Associate,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8926&type=small&showNoImage","displayName":"Sangbin Park","firstName":"Sangbin","href":"http://med.stanford.edu/profiles/Sangbin_Park","researchInterest":""},{"lastName":"Cao","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=11477&type=small&showNoImage","displayName":"Jian Cao","firstName":"Jian","href":"http://med.stanford.edu/profiles/Jian_Cao","researchInterest":""},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/Mickey_Hu","researchInterest":""},{"lastName":"Samos","clinicalFocus":[],"appointments":[{"appointment":"Science Writer/Editor,Neurosurgery"},{"appointment":"Information Editor,Neurosurgery"}],"primaryAppointment":"Science Writer/Editor,Neurosurgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=28093&type=small&showNoImage","displayName":"Cynthia Samos","firstName":"Cynthia","href":"http://med.stanford.edu/profiles/Cynthia_Samos","researchInterest":""},{"lastName":"Ge","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=21246&type=small&showNoImage","displayName":"Xuecai Ge","firstName":"Xuecai","href":"http://med.stanford.edu/profiles/Xuecai_Ge","researchInterest":"I am interested in how the Hedgehog signaling transduction is regulated, and how the mis-regulation of Hedgehog pathway leads to human diseases such as Medulloblastoma."},{"lastName":"Cyert","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6213&type=small&showNoImage","displayName":"Martha Cyert","firstName":"Martha","href":"http://med.stanford.edu/profiles/Martha_Cyert","researchInterest":"Cells respond to extracellular changes by activating signal transduction pathways, many of which are highly conserved. We study Ca2+-mediated signaling in a simple eukaryote, Saccharomyces cerevisiae. Using genetic, genomic, biochemical and cell biological approaches, we are examining how the Ca2+/calmodulin-regulated phosphatase, calcineurin, regulates gene expression and other cellular processes in response to environmental stress."},{"lastName":"Axelrod","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4410&type=small&showNoImage","displayName":"Jeffrey Axelrod","firstName":"Jeffrey","href":"http://med.stanford.edu/profiles/Jeffrey_Axelrod","researchInterest":"Genetic and cell biological analyses of signals controlling cell polarity and morphogenesis.  Frizzled signaling and cytoskeletal organization."},{"lastName":"Jackson","clinicalFocus":[],"appointments":[{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Member,Bio-X","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4463&type=small&showNoImage","displayName":"Peter Jackson","firstName":"Peter","href":"http://med.stanford.edu/profiles/Peter_Jackson","researchInterest":"Cell cycle and cyclin control of DNA replication ."},{"lastName":"Graef","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7247&type=small&showNoImage","displayName":"Isabella Graef","firstName":"Isabella","href":"http://med.stanford.edu/profiles/Isabella_Graef","researchInterest":"We are interested in addressing questions in neuronal development and function by a combination of genetic, cell biological, biochemical and chemical approaches. \r\nThe main focus of our lab is centered around two topics: 1) the interface of signaling and gene regulation in neuronal development, with a focus on calcineurin-NFAT signaling; 2) the development of small molecules, which interfere with protein-protein interactions underlying neurodegenerative diseases."},{"lastName":"Sahoo","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Pathology - Stem Cell Institute"}],"primaryAppointment":"Instructor,Pathology - Stem Cell Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10888&type=small&showNoImage","displayName":"Debashis Sahoo","firstName":"Debashis","href":"http://med.stanford.edu/profiles/Debashis_Sahoo","researchInterest":""}]}