{"result":[{"lastName":"Engleman","clinicalFocus":[{"focus":"Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Professor,Medicine"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4490&type=small&showNoImage","displayName":"Edgar Engleman","firstName":"Edgar","href":"http://med.stanford.edu/profiles/Edgar_Engleman","researchInterest":"Dendritic cells, NK cells and T cells; functional proteins and genes; immunotherapeutic approaches to cancer and autoimmune disease."},{"lastName":"Merritt","clinicalFocus":[{"focus":"Surgery"},{"focus":"Thoracic Surgery"},{"focus":"Surgical Procedures, Minimally Invasive"},{"focus":"VATS Lobectomy"},{"focus":"Laparoscopic Surgical Procedures"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Cardiothoracic Surgery - Thoracic Surgery"}],"primaryAppointment":"Assistant Professor - Med Center Line,Cardiothoracic Surgery - Thoracic Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10438&type=small&showNoImage","displayName":"Robert E. Merritt","firstName":"Robert","href":"http://med.stanford.edu/profiles/Robert_Merritt","researchInterest":""},{"lastName":"Lee","clinicalFocus":[{"focus":"Hematology"},{"focus":"Leukemia - Hematology"}],"appointments":[{"appointment":"Associate Professor,Medicine - Hematology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Medicine - Hematology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4564&type=small&showNoImage","displayName":"Peter P. Lee","firstName":"Peter","href":"http://med.stanford.edu/profiles/Peter_Lee","researchInterest":"Understanding the biology of cancer-T cell interactions."},{"lastName":"Lewis","clinicalFocus":[{"focus":"Infectious Diseases, Pediatric"},{"focus":"Pediatric Infectious Disease"}],"appointments":[{"appointment":"Professor - Med Center Line,Pediatrics - Immunology & Transplant Biology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor - Med Center Line,Pediatrics - Immunology & Transplant Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4439&type=small&showNoImage","displayName":"David B. Lewis","firstName":"David","href":"http://med.stanford.edu/profiles/David_Lewis","researchInterest":"My laboratory has two major research interests.  First, to define cellular and molecular mechanisms that limit T cell responses to vaccines and pathogens during normal early postnatal development and in cases of inherited genetic immunodeficiencies.  Second, to determine how these limitations in immunity can be overcome by using novel approaches for vaccine adjuvants, with a particular focus on anti-viral vaccines."},{"lastName":"Davis","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4282&type=small&showNoImage","displayName":"Mark M. Davis","firstName":"Mark","href":"http://med.stanford.edu/profiles/Mark_Davis","researchInterest":"Molecular mechanisms of lymphocyte recognition and differentiation; molecular genetics and expression of T-cell receptor genes.  Dynamics and functionality of specific T cell populations in human cancer."},{"lastName":"Brody","clinicalFocus":[{"focus":"Burkitt's Lymphoma"},{"focus":"Hodgkin's Disease - Medical Oncology"},{"focus":"Lymphoma "},{"focus":"Non-Hodgkin's Lymphoma"},{"focus":"Oncology"},{"focus":"Oncology (Cancer)"}],"appointments":[{"appointment":"Instructor,Medicine - Oncology"}],"primaryAppointment":"Instructor,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7956&type=small&showNoImage","displayName":"Joshua Brody","firstName":"Joshua","href":"http://med.stanford.edu/profiles/Joshua_Brody","researchInterest":"The focus of my research is on ways to design new and improve upon current cancer vaccines.  A primary approach is to use vaccination to induce anti-cancer T cells, then adoptively transfer those T cells back into the patient after lymphodepletion, such as with chemotherapy or autologous stem cell transplant.  The concept is to thus provide primed immune cells during this lymphodepleted 'window of opportunity' to allow immune reconstitution in a setting that educates it to hate cancer."},{"lastName":"Jiang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10042&type=small&showNoImage","displayName":"Xinguo Jiang","firstName":"Xinguo","href":"http://med.stanford.edu/profiles/Xinguo_Jiang","researchInterest":"My research focuses on microvascular remodeling of airways undergoing rejection, with emphasis on determining the role of recipient-derived angiogenic cells, including endothelial progenitor cells and other angiogenic support cells."},{"lastName":"Fathman","clinicalFocus":[{"focus":"Immunology"},{"focus":"Immunology and Rheumatology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4479&type=small&showNoImage","displayName":"C. Garrison Fathman","firstName":"C","href":"http://med.stanford.edu/profiles/C_Fathman","researchInterest":"My lab of molecular and cellular immunology is interested in research in the general field of T cell activation and autoimmunity.   We use lentiviral mediated transduction of murine dendritic cells with immunoregulatory proteins for site specific and targeted immunotherapy. We have idintified a gene (GRAIL) that seems to control T cell anergy and are defining the regulatory T cell core transcriptome.  Additional studies are on the mechanism of effect of anti-CD3 antibodies in therapy of T1D."},{"lastName":"Pillai","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Medicine - Immunology & Rheumatology"}],"primaryAppointment":"Instructor,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8455&type=small&showNoImage","displayName":"Asha Pillai, MD","firstName":"Asha","href":"http://med.stanford.edu/profiles/Asha_Pillai","researchInterest":"Research:\r\n-- Graft-versus-Host Disease (GVHD) Protective Strategies\r\n-- Innate and Adaptive Regulatory T cells\r\n-- Immunoregulatory Networks after BMT\r\n-- Murine Modelling and Translation of  Strategies for Transplant Tolerance\r\n\r\nClinical:\r\n-- Non-myeloablative BMT strategies \r\n-- Pediatric Bone Marrow/Hematopoietic Stem Cell Transplantation\r\n-- International Development of Hematology/Oncology in India"},{"lastName":"Nolan","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4713&type=small&showNoImage","displayName":"Garry Nolan","firstName":"Garry","href":"http://med.stanford.edu/profiles/Garry_Nolan","researchInterest":"Dr. Nolan's group uses high throughput single cell analysis technology of kinase driven signaling cascades to interrogate autoimmunity, cancer, virology (influenza), bacterial pathogens (Listeria and Salmonella) as well as understanding normal immune system function.  Using advanced flow cytometric techniques and computational biology approaches, we focus on high throughput drug screening, mouse models of disease in patient materials, and understanding disease processes at the single cell level."},{"lastName":"Strober","clinicalFocus":[{"focus":"Immunology and Rheumatology"},{"focus":"Rheumatology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4152&type=small&showNoImage","displayName":"Samuel Strober","firstName":"Samuel","href":"http://med.stanford.edu/profiles/Samuel_Strober","researchInterest":"Mechanisms of immune tolerance; regulatory processes in autoimmunity and transplantation and extrathymic T cell maturation."},{"lastName":"Bonham","clinicalFocus":[{"focus":"General Surgery"},{"focus":"Kidney and Pancreas Transplantation"},{"focus":"Liver Transplantation"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Surgery - Multi-Organ Transplantation"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor - Med Center Line,Surgery - Multi-Organ Transplantation","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3884&type=small&showNoImage","displayName":"Clark Bonham","firstName":"Clark","href":"http://med.stanford.edu/profiles/Clark_Bonham","researchInterest":""},{"lastName":"Krams","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Surgery - Multi-Organ Transplantation"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor (Research),Surgery - Multi-Organ Transplantation","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4475&type=small&showNoImage","displayName":"Sheri Krams","firstName":"Sheri","href":"http://med.stanford.edu/profiles/Sheri_Krams","researchInterest":"We have recently cloned a novel NK cell receptor which is likely involved in the activation of NK cells and are characterizing the expression and effector functions of this receptor in the context of transplantation. In related studies the role of NK cells in alloreactivity is being examined. Pathways of apoptosis, especially the pro-apoptotic molecule BID, is being studied in hepatocytes and allogeneic liver grafts"},{"lastName":"Butte","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Pediatrics - Immunology & Transplant Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Pediatrics - Immunology & Transplant Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=13416&type=small&showNoImage","displayName":"Manish J. Butte, MD PhD","firstName":"Manish","href":"http://med.stanford.edu/profiles/Manish_Butte","researchInterest":""},{"lastName":"Martinez","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Surgery - Multi-Organ Transplantation"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor (Research),Surgery - Multi-Organ Transplantation","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4474&type=small&showNoImage","displayName":"Olivia Martinez","firstName":"Olivia","href":"http://med.stanford.edu/profiles/Olivia_Martinez","researchInterest":"Cell death pathways in EBV B cell lymphomas; role of cytokines and immunosuppression in growth and survival of EBV B cell lymphomas; cytokine pathways in graft rejection; identification of regulatory T cell subsets in alloreactivity; role of co-stimulation in alloreactivity; "},{"lastName":"Negrin","clinicalFocus":[{"focus":"Blood and Marrow Transplantation"},{"focus":"Hematology"}],"appointments":[{"appointment":"Professor,Medicine - Division: Blood and  \r\nMarrow Transplantation"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Medicine - Division: Blood and  \r\nMarrow Transplantation","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4138&type=small&showNoImage","displayName":"Robert Negrin","firstName":"Robert","href":"http://med.stanford.edu/profiles/Robert_Negrin","researchInterest":"Our labaratory focuses on the study of immune recognition by T and NK cells with special emphasis on graft vs host disease and graft vs tumor reactions. We utilize both murine and human systems in an effort to enhance graft vs tumor reactions while controlling graft vs host disease. We have developed bioluminescence models in collaboration with the Contag laboratory to study the trafficking of immune effector cells with a special emphasis on NK, T and regulatory T cells."},{"lastName":"Levy","clinicalFocus":[{"focus":"Lymphoma "},{"focus":"Non-Hodgkin's Lymphoma"},{"focus":"Non-Hodgkin's Lymphoma - Medical Oncology"},{"focus":"Burkitt's Lymphoma"},{"focus":"Burkitt's Lymphoma - Medical Oncology"},{"focus":"Hodgkin's Disease"},{"focus":"Hodgkin's Disease - Medical Oncology"},{"focus":"Burkitt's Lymphoma - Hematology"},{"focus":"Hodgkin's Disease - Hematology"},{"focus":"Oncology"},{"focus":"Oncology (Cancer)"},{"focus":"Non-Hodgkin's Lymphoma - Hematology"}],"appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4608&type=small&showNoImage","displayName":"Ronald Levy, MD","firstName":"Ronald","href":"http://med.stanford.edu/profiles/Ronald_Levy","researchInterest":"Clinical Interests: lymphoma. Research Interests: Immunology and molecular biology of lymphoid malignancy; molecular vaccines for cancer."},{"lastName":"Contag","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Pediatrics - Neonatology"},{"appointment":"Associate Professor,Microbiology & Immunology"},{"appointment":"Associate Professor (By courtesy),Radiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Pediatrics - Neonatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4036&type=small&showNoImage","displayName":"Christopher H. Contag","firstName":"Christopher","href":"http://med.stanford.edu/profiles/Christopher_Contag","researchInterest":"We develop and use the tools of molecular imaging to understand oncogenesis, reveal patterns of cell migration in immunosurveillance, monitor gene expression, visualize stem cell biology, and assess the distribution of pathogens in living animal models of human biology and disease. Biology doesn't occur in \"a vacuum\" or on coated plates--it occurs in the living body and that's were we look for biological patterns and responses to insult."},{"lastName":"Levy","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor (Research),Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4307&type=small&showNoImage","displayName":"Shoshana Levy","firstName":"Shoshana","href":"http://med.stanford.edu/profiles/Shoshana_Levy","researchInterest":"Our research focuses on the mechanism of action of tetraspanins, an evolutionary conserved, widely expressed multi-gene family. We study a prototype, CD81, a molecule implicated in the pathogenesis of two major human diseases: hepatitis C virus (HCV) and malaria."},{"lastName":"Butcher","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4498&type=small&showNoImage","displayName":"Eugene Butcher","firstName":"Eugene","href":"http://med.stanford.edu/profiles/Eugene_Butcher","researchInterest":"Our interests include: \r\n1) The physiology and significance of lymphocyte homing in local and systemic immunity; \r\n2) biochemical and genetic studies of molecules that direct leukocyte recruitment; \r\n3) cellular and molecular genetic studies of leukocyte chemotaxis and the role of chemokines; \r\n4) vascular differentiation in normal and pathologic inflammatory states; \r\n5) systems and chemical biology approaches to understanding the regulation of lymphocyte trafficking programs."},{"lastName":"Higgins","clinicalFocus":[{"focus":"Pathology and Laboratory Medicine"},{"focus":"Anatomic/Clinical Pathology"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor - Med Center Line,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4038&type=small&showNoImage","displayName":"John Higgins","firstName":"John","href":"http://med.stanford.edu/profiles/John_Higgins","researchInterest":"I work as a diagnostic surgical pathologist doing tissue and cDNA microarray-based translational research in renal neoplasia and medical renal disease. Subspecialty areas of clinical interest include diagnostic immunohistochemistry, renal, hepatic and transplant pathology."},{"lastName":"Dosiou","clinicalFocus":[{"focus":"Thyroid Dysfunction in Pregnancy"},{"focus":"Graves' Disease"},{"focus":"Thyroid Nodules"},{"focus":"Hyperthyroidism"},{"focus":"Endocrinology and Metabolism"},{"focus":"Parathyroid Diseases"},{"focus":"Hyperparathyroidism"}],"appointments":[{"appointment":"Clinical Assistant Professor,Medicine - Endocrinology/Gerontology/Metab"}],"primaryAppointment":"Clinical Assistant Professor,Medicine - Endocrinology/Gerontology/Metab","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5882&type=small&showNoImage","displayName":"Chrysoula Dosiou","firstName":"Chrysoula","href":"http://med.stanford.edu/profiles/Chrysoula_Dosiou","researchInterest":"I am highly interested in the interactions between the endocrine and immune systems in women. Current clinical research interests lie in the field of autoimmune thyroid disease, especially thyroid autoimmunity in pregnancy."},{"lastName":"Michie","clinicalFocus":[{"focus":"Anatomic Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4707&type=small&showNoImage","displayName":"Sara Michie","firstName":"Sara","href":"http://med.stanford.edu/profiles/Sara_Michie","researchInterest":"Lymphocyte/endothelial cell adhesion mechanisms involved in lymphocyte migration to sites of inflammation; regulation of expression of endothelial cell adhesion molecules."},{"lastName":"Garcia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Professor,Structural Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4370&type=small&showNoImage","displayName":"Chris Garcia","firstName":"Chris","href":"http://med.stanford.edu/profiles/Chris_Garcia","researchInterest":"Structural and functional studies of transmembrane receptor interactions with their ligands in systems relevant to human health and disease - primarily in immunity, infection, and neurobiology.  We study these problems using protein engineering, structural, biochemical, and combinatorial biology approaches."},{"lastName":"Rosen","clinicalFocus":[{"focus":"Pulmonary Disease"},{"focus":"Pulmonology (Lung) and Critical Care "}],"appointments":[{"appointment":"Associate Professor,Medicine - Pulmonary & Critical Care Med"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Medicine - Pulmonary & Critical Care Med","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4245&type=small&showNoImage","displayName":"Glenn Rosen","firstName":"Glenn","href":"http://med.stanford.edu/profiles/Glenn_Rosen","researchInterest":"Our laboratory examines apoptotic and cell cycle pathways in cancer and lung disease. We have identified a novel cell cycle protein which regulates cell cycle progression in immune cells and the lung.  We are also studying signaling pathways that regulate cancer cell growth and metastasis."}]}