{"result":[{"lastName":"Wyss-Coray","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Neurology & Neurological Sciences"}],"primaryAppointment":"Associate Professor (Research),Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3929&type=small&showNoImage","displayName":"Tony Wyss-Coray","firstName":"Tony","href":"http://med.stanford.edu/profiles/Tony_Wyss-Coray","researchInterest":"Use of genetic and molecular tools to dissect immune and inflammatory pathways in Alzheimer's and neurodegeneration."},{"lastName":"Murphy","clinicalFocus":[{"focus":"Psychiatry"},{"focus":"Geriatric Psychiatry"}],"appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Neurosciences"}],"primaryAppointment":"Professor,Psychiatry & Behavioral Science - Neurosciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4515&type=small&showNoImage","displayName":"Greer Murphy M.D., Ph.D.","firstName":"Greer","href":"http://med.stanford.edu/profiles/Greer_Murphy","researchInterest":"Glial cell neurotoxicity and neuroprotection in Alzheimer's disease. Genome wide expression analysis of mouse models for Alzheimer's disease. Pharmacogenetics of mood disorders and nicotine addiction."},{"lastName":"Stearns","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6244&type=small&showNoImage","displayName":"Tim Stearns","firstName":"Tim","href":"http://med.stanford.edu/profiles/Tim_Stearns","researchInterest":"We use the tools of genetics, microscopy, and biochemistry to understand fundamental questions of cell biology: How are cells organized by the cytoskeleton? How does the cytoskeleton effect chromosome segretation with high fidelity? How is cell division coordinated with duplication of the centrosome, and what goes wrong in cancer cells defective in this coordination?"},{"lastName":"Ferrell","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4656&type=small&showNoImage","displayName":"James Ferrell","firstName":"James","href":"http://med.stanford.edu/profiles/James_Ferrell","researchInterest":"My lab has two main goals: to understand mitotic regulation and to understand the systems-level logic of simple signaling circuits.  We often make use of Xenopus laevis oocytes, eggs, and cell-free extracts for both sorts of study.  We also carry out single-cell fluorescence imaging studies on mammalian cell lines."},{"lastName":"Villeneuve","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4035&type=small&showNoImage","displayName":"Anne Villeneuve","firstName":"Anne","href":"http://med.stanford.edu/profiles/Anne_Villeneuve","researchInterest":"Mechanisms underlying homologous chromosome pairing, DNA recombination and chromosome remodeling during meiosis, using the nematode Caenorhabditis elegans as an experimental system.  High-resolution 3-D imaging of dynamic reorganization of chromosome architecture.  Role of protease inhibitors in regulating sperm activation."},{"lastName":"Fuller","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4159&type=small&showNoImage","displayName":"Margaret T. Fuller","firstName":"Margaret","href":"http://med.stanford.edu/profiles/Margaret_Fuller","researchInterest":"Regulation of stem cell division and self-renewal Cell type specific transcription machinery and regulation of cell differentiation Developmental regulation of cell cycle progression during male meiosis Molecular dissection of the mechanism of cytokinesis."},{"lastName":"LeMieux","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Chemical Engineering"}],"primaryAppointment":"Postdoctoral Research fellow, Chemical Engineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8779&type=small&showNoImage","displayName":"Melbs LeMieux","firstName":"Melburne","href":"http://med.stanford.edu/profiles/Melburne_LeMieux","researchInterest":"Development and nanoscale assembly of carbon nanotubes and related nanomaterials for electronic and energy applications."},{"lastName":"Graef","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7247&type=small&showNoImage","displayName":"Isabella Graef","firstName":"Isabella","href":"http://med.stanford.edu/profiles/Isabella_Graef","researchInterest":"We are interested in addressing questions in neuronal development and function by a combination of genetic, cell biological, biochemical and chemical approaches. \r\nThe main focus of our lab is centered around two topics: 1) the interface of signaling and gene regulation in neuronal development, with a focus on calcineurin-NFAT signaling; 2) the development of small molecules, which interfere with protein-protein interactions underlying neurodegenerative diseases."},{"lastName":"Tinklenberg","clinicalFocus":[],"appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - VA & Geriatric"}],"primaryAppointment":"Professor,Psychiatry & Behavioral Science - VA & Geriatric","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4107&type=small&showNoImage","displayName":"Jared Tinklenberg","firstName":"Jared","href":"http://med.stanford.edu/profiles/Jared_Tinklenberg","researchInterest":"Psychopharmacology of dementia and Alzheimer's disease;, biological correlates of Alzheimer's disease; sexual dysfunction in, Alzheimer's disease; memory disorders."},{"lastName":"Roth","clinicalFocus":[],"appointments":[{"appointment":"Emeritus (Active) Professor,Chemical and Systems Biology"}],"primaryAppointment":"Emeritus (Active) Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4175&type=small&showNoImage","displayName":"Richard Roth","firstName":"Richard","href":"http://med.stanford.edu/profiles/Richard_Roth","researchInterest":"Insulin is one of the primary regulators of rapid anabolic responses in the body. Defects in the synthesis and/or ability of cells to respond to insulin results in the condition known as diabetes mellitus. To better design methods of treatment for this disorder, we have been focusing our research on how insulin elicits its various biological responses."},{"lastName":"Jackson","clinicalFocus":[],"appointments":[{"appointment":"Member,Cancer Center"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Member,Cancer Center","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4463&type=small&showNoImage","displayName":"Peter Jackson","firstName":"Peter","href":"http://med.stanford.edu/profiles/Peter_Jackson","researchInterest":"Cell cycle and cyclin control of DNA replication ."},{"lastName":"Straight","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Biochemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Assistant Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6006&type=small&showNoImage","displayName":"Aaron Straight","firstName":"Aaron","href":"http://med.stanford.edu/profiles/Aaron_Straight","researchInterest":"We study the process of cell division. Our research is focused on understanding how chromosomes are segregated during mitosis and how cells divide during cytokinesis."},{"lastName":"Velandy Chodaparambil","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Structural Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9946&type=small&showNoImage","displayName":"Jay Chodaparambil","firstName":"Jayanth","href":"http://med.stanford.edu/profiles/Jayanth_Velandy Chodaparambil","researchInterest":""},{"lastName":"Brunet","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Assistant Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6012&type=small&showNoImage","displayName":"Anne Brunet","firstName":"Anne","href":"http://med.stanford.edu/profiles/Anne_Brunet","researchInterest":"Our lab studies the molecular basis of longevity. We are interested in the mechanism of action of known longevity genes, including FOXO and SIRT, in the mammalian nervous system. We are particularly interested in the role of these longevity genes in neural stem cells. We are also discovering novel genes and processes involved in aging using two model systems, the invertebrate C. elegans and an extremely short-lived vertebrate, the African killifish N. furzeri."},{"lastName":"Wysocka","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Chemical and Systems Biology"},{"appointment":"Assistant Professor,Developmental Biology"}],"primaryAppointment":"Assistant Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7764&type=small&showNoImage","displayName":"Joanna Wysocka","firstName":"Joanna","href":"http://med.stanford.edu/profiles/Joanna_Wysocka","researchInterest":"Research in our lab focuses on mechanisms of epigenetic regulation in differentiation and development. In particular, we are studying the function of histone modifying enzymes in embryonic stem cell self-renewal and in early cell fate decisions. We are interested in the role of chromatin modifications in establishment and maintenance of gene expression patterns during normal and pathological development, and in nuclear reprogramming."},{"lastName":"Crabtree","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4283&type=small&showNoImage","displayName":"Gerald Crabtree","firstName":"Gerald","href":"http://med.stanford.edu/profiles/Gerald_Crabtree","researchInterest":"The role of chromatin in stem cell formation and function.  Development of small molecule regulators as experimental probes and therapeutic leads.  Signaling through calcineurin  and NFAT in vertebrate development."},{"lastName":"Gozani","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Assistant Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6423&type=small&showNoImage","displayName":"Or Gozani","firstName":"Or","href":"http://med.stanford.edu/profiles/Or_Gozani","researchInterest":"We study the molecular mechanisms by which chromatin-signaling networks effect nuclear and epigenetic programs, and how dysregulation of these pathways leads to disease.  Our work centers on the biology of lysine methylation, a principal chromatin-regulatory mechanism that directs epigenetic processes.  We study how lysine methylation events are generated, sensed, and transduced, and how these chemical marks integrate with other nuclear signaling systems to govern diverse cellular functions."},{"lastName":"Yoo","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pathology"}],"primaryAppointment":"Postdoctoral Research fellow, Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10159&type=small&showNoImage","displayName":"Andrew Yoo","firstName":"Andrew","href":"http://med.stanford.edu/profiles/Andrew_Yoo","researchInterest":""},{"lastName":"Cimprich","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Chemical and Systems Biology"},{"appointment":"Associate Professor (By courtesy),Chemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4417&type=small&showNoImage","displayName":"Karlene Cimprich","firstName":"Karlene","href":"http://med.stanford.edu/profiles/Karlene_Cimprich","researchInterest":"The use of genetic, biochemical and chemical approaches to understand the DNA damage-induced cell cycle checkpoints and the processes that contribute to maintenance of genomic stability."},{"lastName":"Francke","clinicalFocus":[{"focus":"Clinical Genetics"},{"focus":"Neurogenetics"}],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Professor,Pediatrics"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4281&type=small&showNoImage","displayName":"Uta Francke","firstName":"Uta","href":"http://med.stanford.edu/profiles/Uta_Francke","researchInterest":"Functional consequences and pathogenetic mechanisms of mutations and microdeletions in human neurogenetic syndromes and mouse models: Williams-Beuren syndrome, a heterozygous 1.6 megabase deletion; Rett syndrome, caused by mutations in the X-linked methyl-CpG binding protein 2 (MECP2) gene. Mechanisms of genomic imprinting: Prader Willi syndrome"},{"lastName":"Lorch","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Structural Biology"}],"primaryAppointment":"Associate Professor (Research),Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4116&type=small&showNoImage","displayName":"Yahli Lorch","firstName":"Yahli","href":"http://med.stanford.edu/profiles/Yahli_Lorch","researchInterest":""},{"lastName":"Carroll","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biochemistry"}],"primaryAppointment":"Postdoctoral Research fellow, Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9403&type=small&showNoImage","displayName":"Christopher Carroll","firstName":"Christopher","href":"http://med.stanford.edu/profiles/Christopher_Carroll","researchInterest":""},{"lastName":"Vrljic","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology"}],"primaryAppointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8903&type=small&showNoImage","displayName":"Marija Vrljic","firstName":"Marija","href":"http://med.stanford.edu/profiles/Marija_Vrljic","researchInterest":""},{"lastName":"Zhan","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8986&type=small&showNoImage","displayName":"Ke Zhan","firstName":"Ke","href":"http://med.stanford.edu/profiles/Ke_Zhan","researchInterest":""},{"lastName":"Lazzeroni","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Psychiatry & Behavioral Science"},{"appointment":"Associate Professor (Research),Pediatrics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor (Research),Psychiatry & Behavioral Science","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4220&type=small&showNoImage","displayName":"Laura C. Lazzeroni, Ph.D.","firstName":"Laura","href":"http://med.stanford.edu/profiles/Laura_Lazzeroni","researchInterest":""}]}