{"result":[{"lastName":"Felsher","clinicalFocus":[{"focus":"Hodgkin's Disease"},{"focus":"Hodgkin's Disease - Hematology"},{"focus":"Hodgkin's Disease - Medical Oncology"},{"focus":"Lymphoma "},{"focus":"Oncology"},{"focus":"Oncology (Cancer)"}],"appointments":[{"appointment":"Associate Professor,Medicine - Oncology"},{"appointment":"Associate Professor,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5931&type=small&showNoImage","displayName":"Dean W. Felsher","firstName":"Dean","href":"http://med.stanford.edu/profiles/Dean_Felsher","researchInterest":"My laboratory investigates how oncogenes initiate and sustain tumorigenesis. I have developed model systems whereby I can conditionally activate oncogenes in normal human and mouse cells in tissue culture or in specific tissues of transgenic mice. In particular using the tetracycline regulatory system, I have generated a conditional model system for MYC-induced tumors. I have shown that cancers caused by the conditional over-expression of the MYC proto-oncogene regress with its inactivation."},{"lastName":"Fan","clinicalFocus":[{"focus":"Medical Oncology"},{"focus":"Oncology (Cancer)"}],"appointments":[{"appointment":"Instructor,Medicine - Oncology"}],"primaryAppointment":"Instructor,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7543&type=small&showNoImage","displayName":"Alice Fan","firstName":"Alice","href":"http://med.stanford.edu/profiles/Alice_Fan","researchInterest":"Dr. Fan studies how turning off oncogenes (cancer genes) can cause tumor regression in preclinical and clinical studies. Based on preclinical findings, she has initiated a clinical trial studying atorvastatin for the treatment of patients with certain non-Hodgkin's lymphomas. In the laboratory, she also uses preclinical models of cancer to validate new nanotechnology strategies for tumor diagnosis and treatment."},{"lastName":"Sylvester","clinicalFocus":[{"focus":"Pediatric Surgery"},{"focus":"Surgery, Pediatric"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Surgery - Pediatric Surgery"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor - Med Center Line,Surgery - Pediatric Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3827&type=small&showNoImage","displayName":"Karl Sylvester","firstName":"Karl","href":"http://med.stanford.edu/profiles/Karl_Sylvester","researchInterest":"Current research interests include mesenchymal stem cell biology, clonal isolation of mesenchymal progenitors, signaling pathways for maintenance of potency and committment to differentiation.\r\n\r\nAdditional areas of ongoing study are the mechanisms of liver regeneration.  Interests include local and humoral cellular components of liver repair and regrowth; and the requisite cellular signaling mechanisms of liver stem cell biology."},{"lastName":"Park","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pediatrics"}],"primaryAppointment":"Postdoctoral Research fellow, Pediatrics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9501&type=small&showNoImage","displayName":"Kwon-Sik Park","firstName":"Kwon-Sik","href":"http://med.stanford.edu/profiles/Kwon-Sik_Park","researchInterest":""},{"lastName":"Rosen","clinicalFocus":[{"focus":"Pulmonary Disease"},{"focus":"Pulmonology (Lung) and Critical Care "}],"appointments":[{"appointment":"Associate Professor,Medicine - Pulmonary & Critical Care Med"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Medicine - Pulmonary & Critical Care Med","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4245&type=small&showNoImage","displayName":"Glenn Rosen","firstName":"Glenn","href":"http://med.stanford.edu/profiles/Glenn_Rosen","researchInterest":"Our laboratory examines apoptotic and cell cycle pathways in cancer and lung disease. We have identified a novel cell cycle protein which regulates cell cycle progression in immune cells and the lung.  We are also studying signaling pathways that regulate cancer cell growth and metastasis."},{"lastName":"Sweet-Cordero","clinicalFocus":[{"focus":"Pediatric Hematology-Oncology"}],"appointments":[{"appointment":"Assistant Professor,Pediatrics - Cancer Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Assistant Professor,Pediatrics - Cancer Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6970&type=small&showNoImage","displayName":"Alejandro Sweet-Cordero","firstName":"Alejandro","href":"http://med.stanford.edu/profiles/Alejandro_Sweet-Cordero","researchInterest":"Our laboratory is devoted to the analysis of pathways involved in the initiation, progression, and maintenance of cancer.   Utilizing the mouse as a model system, we strive to understand aberrant oncogenic signaling, the role of the tumor microenvironment and the mechanisms involved in chemotherapy response and resistance at the molecular, cellular, and organismal levels."},{"lastName":"Shachaf","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Microbiology & Immunology - Baxter Laboratory"}],"primaryAppointment":"Instructor,Microbiology & Immunology - Baxter Laboratory","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7574&type=small&showNoImage","displayName":"Catherine Shachaf","firstName":"Catherine","href":"http://med.stanford.edu/profiles/Catherine_Shachaf","researchInterest":"The focus of our research is to determine the genomic and proteomic signatures of a cancer cell, and to compare them to the signatures of normal stem cells.  The goal is to identify the pathway(s) that determine the fate of a progenitor cell \u0096 to become neoplastic or to remain normal \u0096 then to prevent the neoplastic pathway decision.\r\n\r\nWe are also developing surface enhanced Raman (SERS) nanoparticles to supplement the fluorescent molecules currently available for flow cytometry."},{"lastName":"Noonan","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10537&type=small&showNoImage","displayName":"Emily Noonan Ph.D.","firstName":"Emily","href":"http://med.stanford.edu/profiles/Emily_Noonan","researchInterest":"chemoprevetion, HDAC inhibitors, miRNAs, tumor suppressor genes"},{"lastName":"Van de Rijn","clinicalFocus":[{"focus":"Pathology and Laboratory Medicine"},{"focus":"Anatomic/Clinical Pathology"}],"appointments":[{"appointment":"Professor - Med Center Line,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor - Med Center Line,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4008&type=small&showNoImage","displayName":"Matt Van de Rijn","firstName":"Matt","href":"http://med.stanford.edu/profiles/Matt_Van de Rijn","researchInterest":"Our research focuses on gene microarray analysis of human soft tissue tumors (sarcomas). In addition we work with tissue microarrays to characterize large numbers of novel antisera raised against peptides derived from genes found to be of interest during gene array analysis."},{"lastName":"Kwei","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pathology"}],"primaryAppointment":"Postdoctoral Research fellow, Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8824&type=small&showNoImage","displayName":"Kevin Kwei","firstName":"Kevin","href":"http://med.stanford.edu/profiles/Kevin_Kwei","researchInterest":""},{"lastName":"Pollack","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6066&type=small&showNoImage","displayName":"Jonathan Pollack","firstName":"Jonathan","href":"http://med.stanford.edu/profiles/Jonathan_Pollack","researchInterest":"Our laboratory uses genomics approaches to explore patterns of gene expression and gene copy number alteration in both human cancer cell line model systems and in tumors, with the goals of better understanding cancer, and developing novel diagnostic and therapeutic strategies."},{"lastName":"West","clinicalFocus":[{"focus":"Pathology and Laboratory Medicine"},{"focus":"Breast Cancer"},{"focus":"Sarcoma"},{"focus":"Anatomic/Clinical Pathology"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Pathology"}],"primaryAppointment":"Assistant Professor - Med Center Line,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3910&type=small&showNoImage","displayName":"Robert West","firstName":"Robert","href":"http://med.stanford.edu/profiles/Robert_West","researchInterest":"My laboratory studies the molecular events that lead to and sustain tumorigenesis in soft tissue tumors.  We also have an interest in stromal reaction patterns in the microenvironment of cancer."},{"lastName":"Sen","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Dermatology"}],"primaryAppointment":"Postdoctoral Research fellow, Dermatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10169&type=small&showNoImage","displayName":"George Sen","firstName":"George","href":"http://med.stanford.edu/profiles/George_Sen","researchInterest":""},{"lastName":"Whyte","clinicalFocus":[{"focus":"Cardiothoracic Surgery"},{"focus":"Esophageal Cancer - Thoracic Surgery"},{"focus":"Heart and Lung Transplantation"},{"focus":"Lung Cancer - Thoracic Surgery"},{"focus":"Mesothelioma "},{"focus":"Mesothelioma - Thoracic Surgery"},{"focus":"Thoracic Cancers"},{"focus":"Thoracic Cancers - Thoracic Surgery"},{"focus":"Thoracic Surgery"},{"focus":"Thymoma   "},{"focus":"Thymoma - Thoracic Surgery"}],"appointments":[{"appointment":"Professor - Med Center Line,Cardiothoracic Surgery - Thoracic Surgery"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor - Med Center Line,Cardiothoracic Surgery - Thoracic Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4435&type=small&showNoImage","displayName":"Richard Whyte","firstName":"Richard","href":"http://med.stanford.edu/profiles/Richard_Whyte","researchInterest":"clinical lung and esophageal cancer treatment studies, lung transplantation, surgical ,management of emphysema."},{"lastName":"Chang","clinicalFocus":[{"focus":"Dermatology"}],"appointments":[{"appointment":"Associate Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Dermatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6089&type=small&showNoImage","displayName":"Howard Y. Chang","firstName":"Howard","href":"http://med.stanford.edu/profiles/Howard_Chang","researchInterest":"The Chang group is focused on two fundamental questions in epithelial biology: (1) the basis of positional identities in epidermal structures throughout the body, and (2) how those signals and boundaries may be abrogated to allow cancer metastasis. We are investigating the roles of site-specific fibroblast differentiation in patterning the epidermis, and dissecting the mechanisms of wound healing programs in cancer metastasis."},{"lastName":"Boxer","clinicalFocus":[{"focus":"Hematology"},{"focus":"Multiple Myeloma"},{"focus":"Multiple Myeloma - Medical Oncology"},{"focus":"Plasmacytoma"},{"focus":"Plasmacytoma - Hematology"},{"focus":"Plasmacytoma - Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Hematology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Medicine - Hematology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4658&type=small&showNoImage","displayName":"Linda Boxer","firstName":"Linda","href":"http://med.stanford.edu/profiles/Linda_Boxer","researchInterest":"Regulation of expression of oncogenes in normal and malignant hematologic cells."},{"lastName":"Holgado-Madruga","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Neurosurgery"}],"primaryAppointment":"Instructor,Neurosurgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7072&type=small&showNoImage","displayName":"Marina Holgado-Madruga","firstName":"Maria","href":"http://med.stanford.edu/profiles/Maria_Holgado-Madruga","researchInterest":""},{"lastName":"Wakelee","clinicalFocus":[{"focus":"Investigational Therapeutics"},{"focus":"Lung Cancer - Medical Oncology"},{"focus":"Medical Oncology"},{"focus":"Mesothelioma "},{"focus":"Mesothelioma - Medical Oncology"},{"focus":"Oncology (Cancer)"},{"focus":"Thoracic Cancers"},{"focus":"Thoracic Cancers - Medical Oncology"},{"focus":"thymoma"},{"focus":"thymic carcinoma"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Medicine - Oncology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Assistant Professor - Med Center Line,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6058&type=small&showNoImage","displayName":"Heather Wakelee","firstName":"Heather","href":"http://med.stanford.edu/profiles/Heather_Wakelee","researchInterest":"Dr. Wakelee's research is focused on clinical trials in lung cancer patients.  She also works with novel agents for all malignancies as part of the developmental therapeutics group of the cancer center."},{"lastName":"Giaccia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Radiation Oncology - Radiation Biology"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Radiation Oncology - Radiation Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4141&type=small&showNoImage","displayName":"Amato Giaccia","firstName":"Amato","href":"http://med.stanford.edu/profiles/Amato_Giaccia","researchInterest":"Cellular response to hypoxia and ionizing radiation; cell-cycle control, apoptosis and angiogenesis in transformed cells."},{"lastName":"Finger","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Radiation Oncology"}],"primaryAppointment":"Postdoctoral Research fellow, Radiation Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10597&type=small&showNoImage","displayName":"Elizabeth Finger","firstName":"Elizabeth","href":"http://med.stanford.edu/profiles/Elizabeth_Finger","researchInterest":""},{"lastName":"Koong","clinicalFocus":[{"focus":"Colorectal Cancer"},{"focus":"Colorectal Cancer - Radiation Oncology"},{"focus":"Esophageal Cancer"},{"focus":"Esophageal Cancer - Radiation Oncology"},{"focus":"Liver Cancer"},{"focus":"Liver Cancer - Radiation Oncology"},{"focus":"Pancreatic Cancer "},{"focus":"Pancreatic Cancer - Radiation Oncology"},{"focus":"Radiation Oncology"},{"focus":"Rectal Cancer "},{"focus":"Rectal Cancer - Radiation Oncology"},{"focus":"Stomach Cancer "},{"focus":"Stomach Cancer - Radiation Oncology"}],"appointments":[{"appointment":"Assistant Professor,Radiation Oncology - Radiation Therapy"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Assistant Professor,Radiation Oncology - Radiation Therapy","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4729&type=small&showNoImage","displayName":"Albert Koong","firstName":"Albert","href":"http://med.stanford.edu/profiles/Albert_Koong","researchInterest":"The focus of my laboratory is to understand the role of hypoxia and the tumor microenvironment on malignant progression. My clinical area of interest is in the application of chemoradiotherapy and stereotactic radiosurgery for GI maligancies"},{"lastName":"Upadhyay","clinicalFocus":[{"focus":"Lung Cancer, Solitary Pulmonary Nodule"},{"focus":"Asthma, Adult"},{"focus":"Pulmonology (Lung) and Critical Care "},{"focus":"Pulmonary Medicine"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Medicine - Pulmonary & Critical Care Med"}],"primaryAppointment":"Assistant Professor - Med Center Line,Medicine - Pulmonary & Critical Care Med","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6147&type=small&showNoImage","displayName":"Daya Upadhyay","firstName":"Daya","href":"http://med.stanford.edu/profiles/Daya_Upadhyay","researchInterest":"Dr. Upadhyay examines the molecular link between \u0091Airway Inflammation and Lung Cancer\u0092. We study nicotine stimulation-induced genes that cause escape from oxidative stress mediated Lung Senescence and development of lung cancer and cancer stem cells, and utilizes microRNA analysis for early diagnose of lung cancer in COPD/ smokers. By using exhaled breath condensates and human airway tissue, we examine the genes regulating airway inflammation in a complex duo of \u0091Asthma and obesity\u0092."},{"lastName":"Wong","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurosurgery"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Neurosurgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7143&type=small&showNoImage","displayName":"Albert J. Wong, M.D.","firstName":"Albert","href":"http://med.stanford.edu/profiles/Albert_Wong","researchInterest":"Our goal is to define targets for cancer therapeutics by identifying alterations in signal transduction proteins. We first identified a naturally occurring  mutant EGF receptor (EGFRvIII) and then delineated its unique signal transduction pathway. This work led to the identification of Gab1 followed by the discovery that JNK is constitutively active in tumors. We intiated using altered proteins as the target for vaccination, where an EGFRvIII based vaccine appears to be highly effective."},{"lastName":"Rouse","clinicalFocus":[{"focus":"Pathology and Laboratory Medicine"},{"focus":"Anatomic/Clinical Pathology"}],"appointments":[{"appointment":"Professor - Med Center Line,Pathology"}],"primaryAppointment":"Professor - Med Center Line,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4491&type=small&showNoImage","displayName":"Robert V Rouse","firstName":"Robert","href":"http://med.stanford.edu/profiles/Robert_Rouse","researchInterest":"My recent research efforts are currently focused in the field of applications of immunohistology to the diagnosis of human neoplasms. This work is predominantly aimed at characterizing markers for the identification of non-lymphoid neoplasms and at establishing criteria for their evaluation in diagnostic situations."},{"lastName":"Razorenova","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Radiation Oncology"}],"primaryAppointment":"Postdoctoral Research fellow, Radiation Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9869&type=small&showNoImage","displayName":"Olga Razorenova","firstName":"Olga","href":"http://med.stanford.edu/profiles/Olga_Razorenova","researchInterest":""}]}