{"result":[{"lastName":"Weissman","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology - Stem Cell Institute"},{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor (By courtesy),Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Pathology - Stem Cell Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4605&type=small&showNoImage","displayName":"Irving Weissman","firstName":"Irving","href":"http://med.stanford.edu/profiles/Irving_Weissman","researchInterest":"Stem cell and cancer stem cell biology; development of T and B lymphocytes; cell-surface receptors for oncornaviruses in leukemia. Hematopoietic stem cells; Lymphocyte homing, lymphoma invasiveness and metastasis."},{"lastName":"Clarke","clinicalFocus":[{"focus":"Colorectal Cancer"},{"focus":"Oncology"},{"focus":"Oncology (Cancer)"}],"appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7126&type=small&showNoImage","displayName":"Michael F. Clarke, M.D.","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Clarke","researchInterest":"Dr. Michael F. Clarke is the Associate Director of the Stanford Institute for Stem Cell and Regenerative Medicine.  In addition to his clinical duties in the division of Oncology, Dr. Clarke maintains a laboratory  focused on two areas of research: i) the control of self-renewal of normal stem cells and their malignant counterparts; and ii) the identification and characterization of cancer stem cells. A central issue in stem cell biology is to understand the mechanisms that regulate self-renewa"},{"lastName":"Park","clinicalFocus":[{"focus":"Pathology"},{"focus":"Anatomic/Clinical Pathology"}],"appointments":[{"appointment":"Instructor,Pathology - Stem Cell Institute"}],"primaryAppointment":"Instructor,Pathology - Stem Cell Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6673&type=small&showNoImage","displayName":"Christopher Park","firstName":"Christopher","href":"http://med.stanford.edu/profiles/Christopher_Park","researchInterest":""},{"lastName":"Artandi","clinicalFocus":[{"focus":"Medical Oncology"}],"appointments":[{"appointment":"Associate Professor,Medicine - Hematology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Medicine - Hematology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3848&type=small&showNoImage","displayName":"Steven Artandi","firstName":"Steven","href":"http://med.stanford.edu/profiles/Steven_Artandi","researchInterest":"Telomeres are nucleoprotein complexes that protect chromosome ends and shorten with cell division and aging.  We are interested in how telomere shortening influences cancer, stem cell function and genomic stability.  Telomerase is a reverse transcriptase that synthesizes telomere repeats and is expressed in stem cells and in cancer.  We have found that telomerase also regulates stem cells and we are pursuing the function of telomerase through diverse genetic and biochemical approaches."},{"lastName":"Sahoo","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Pathology - Stem Cell Institute"}],"primaryAppointment":"Instructor,Pathology - Stem Cell Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10888&type=small&showNoImage","displayName":"Debashis Sahoo","firstName":"Debashis","href":"http://med.stanford.edu/profiles/Debashis_Sahoo","researchInterest":""},{"lastName":"Choi","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=13431&type=small&showNoImage","displayName":"Jinkuk Choi","firstName":"Jinkuk","href":"http://med.stanford.edu/profiles/Jinkuk_Choi","researchInterest":""},{"lastName":"Herzenberg","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Genetics"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor (Research),Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6113&type=small&showNoImage","displayName":"Leonore A. Herzenberg","firstName":"Leonore","href":"http://med.stanford.edu/profiles/Leonore_Herzenberg","researchInterest":"B-cell development; Ig rearrangement and repertoire analysis; T cell regulation of antibody\u000bresponses; T cell subsets; glutathione regulation of HIV disease progression; Fluorescence-Activated Cell Sorting (FACS) related software development and gene arrays."},{"lastName":"Majeti","clinicalFocus":[{"focus":"Hematology"}],"appointments":[{"appointment":"Assistant Professor,Medicine - Hematology"}],"primaryAppointment":"Assistant Professor,Medicine - Hematology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8250&type=small&showNoImage","displayName":"Ravindra Majeti","firstName":"Ravindra","href":"http://med.stanford.edu/profiles/Ravindra_Majeti","researchInterest":""},{"lastName":"Cimprich","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Chemical and Systems Biology"},{"appointment":"Associate Professor (By courtesy),Chemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4417&type=small&showNoImage","displayName":"Karlene Cimprich","firstName":"Karlene","href":"http://med.stanford.edu/profiles/Karlene_Cimprich","researchInterest":"The use of genetic, biochemical and chemical approaches to understand the DNA damage-induced cell cycle checkpoints and the processes that contribute to maintenance of genomic stability."},{"lastName":"Herzenberg","clinicalFocus":[],"appointments":[{"appointment":"Emeritus (Active) Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Emeritus (Active) Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4151&type=small&showNoImage","displayName":"Leonard Herzenberg","firstName":"Leonard","href":"http://med.stanford.edu/profiles/Leonard_Herzenberg","researchInterest":"Gene Regulation; Molecular Immunology; Lymphocyte subsets; Fluorescence-Activated Cell\u000bSorter (FACS) development; AIDS; Apoptosis; Redox Regulation; Gene Arrays; and the theraphy of AIDS using the anti-oxidant N'acetylcysteine(NAC)."},{"lastName":"Hanawalt","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5957&type=small&showNoImage","displayName":"Philip Hanawalt","firstName":"Philip","href":"http://med.stanford.edu/profiles/Philip_Hanawalt","researchInterest":"Hanawalt has been a productive researcher in the field of DNA repair since his pioneering discovery of repair replication in E. coli in 1963. He also first demonstrated repair replication in mycoplasmata and in a eukaryote and he has developed a number of important experimental approaches for studying repair, beginning with the BrdUrd density labeling method for resolving semiconservatively replicated DNA from parental DNA containing repair patches. Hanawalt\u0092s approach was used to validate the "},{"lastName":"Blankenberg","clinicalFocus":[{"focus":"Diagnostic Radiology"},{"focus":"Radiology"},{"focus":"Radiology, Pediatric"}],"appointments":[{"appointment":"Associate Professor,Radiology"},{"appointment":"Associate Professor (By courtesy),Pediatrics"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4065&type=small&showNoImage","displayName":"Francis Blankenberg","firstName":"Francis","href":"http://med.stanford.edu/profiles/Francis_Blankenberg","researchInterest":"Studies on apoptotic cell death in vivo using the H MRS phenomenon."},{"lastName":"Dalerba","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Medicine - Oncology"}],"primaryAppointment":"Instructor,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9693&type=small&showNoImage","displayName":"Piero Dalerba","firstName":"Piero","href":"http://med.stanford.edu/profiles/Piero_Dalerba","researchInterest":"Cancer Stem Cells, Colon Cancer"},{"lastName":"Tan","clinicalFocus":[{"focus":"Pathology"},{"focus":"Anatomic/Clinical Pathology"}],"appointments":[{"appointment":"Clinical Assistant Professor,Pathology"}],"primaryAppointment":"Clinical Assistant Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6772&type=small&showNoImage","displayName":"Brent Tan","firstName":"Brent","href":"http://med.stanford.edu/profiles/Brent_Tan","researchInterest":"My research interest is in the use of molecular methods to understand and characterize hematopoietic neoplasms.  My current work focuses on the use of PCR-based assays for clonal rearrangements in the immunoglobulin heavy chain gene (IGH) and T-cell receptor gene (TCR) for the diagnosis of mature T-cell lymphomas."},{"lastName":"Dosiou","clinicalFocus":[{"focus":"Thyroid Dysfunction in Pregnancy"},{"focus":"Graves' Disease"},{"focus":"Thyroid Nodules"},{"focus":"Hyperthyroidism"},{"focus":"Endocrinology and Metabolism"},{"focus":"Parathyroid Diseases"},{"focus":"Hyperparathyroidism"}],"appointments":[{"appointment":"Clinical Assistant Professor,Medicine - Endocrinology/Gerontology/Metab"}],"primaryAppointment":"Clinical Assistant Professor,Medicine - Endocrinology/Gerontology/Metab","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5882&type=small&showNoImage","displayName":"Chrysoula Dosiou","firstName":"Chrysoula","href":"http://med.stanford.edu/profiles/Chrysoula_Dosiou","researchInterest":"I am highly interested in the interactions between the endocrine and immune systems in women. Current clinical research interests lie in the field of autoimmune thyroid disease, especially thyroid autoimmunity in pregnancy."},{"lastName":"Kraft","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Pathology - Stem Cell Institute"}],"primaryAppointment":"Instructor,Pathology - Stem Cell Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7184&type=small&showNoImage","displayName":"Daniel Kraft, MD","firstName":"Daniel","href":"http://med.stanford.edu/profiles/Daniel_Kraft","researchInterest":"-Stem cell biology & Regenerative Medicine\r\n\r\n-Stem Cell Derived Immunotherapy for Cancer\r\n\r\n-BioEngineering\r\n\r\n-The hematopoietic stem cell niche in murine and human systems\r\n\r\n-Human T cell differentiation\r\n\r\n-Humanized animal models\r\n\r\n-Clinical focus: Bone Marrow/Hematopoietic Stem cell transplantation for malignant and non-malignant diseases in adults & children\r\n\r\n-Medical devices to enable stem cell based regenerative medicine, to include marrow derived stem cell harvest, processing and delivery"},{"lastName":"Chu","clinicalFocus":[{"focus":"Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Oncology"},{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4149&type=small&showNoImage","displayName":"Gilbert Chu","firstName":"Gilbert","href":"http://med.stanford.edu/profiles/Gilbert_Chu","researchInterest":"Our laboratory focuses on understanding how cells respond to DNA damage. Our research currently involves areas that interact with each other: repair of radiation damage, and transcriptional responses to DNA damage."},{"lastName":"Strober","clinicalFocus":[{"focus":"Immunology and Rheumatology"},{"focus":"Rheumatology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4152&type=small&showNoImage","displayName":"Samuel Strober","firstName":"Samuel","href":"http://med.stanford.edu/profiles/Samuel_Strober","researchInterest":"Mechanisms of immune tolerance; regulatory processes in autoimmunity and transplantation and extrathymic T cell maturation."},{"lastName":"Parnes","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4487&type=small&showNoImage","displayName":"Jane Parnes","firstName":"Jane","href":"http://med.stanford.edu/profiles/Jane_Parnes","researchInterest":"The lab is studying the mechanisms controlling B cell responsiveness and the balance between tolerance and autoimmunity.  B cells deficient in CD72 are hyperresponsive to stimulation through the B cell receptor.  We are examining the alterations in B cell signaling in these B cells and the mechanisms by which CD72 deficiency partially abrogates anergic tolerance.  We hope to learn how deficiency in CD72 leads to spontaneous autoimmunity and increased susceptibility to induced autoimmune disease."},{"lastName":"Chang","clinicalFocus":[{"focus":"Dermatology"}],"appointments":[{"appointment":"Associate Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Dermatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6089&type=small&showNoImage","displayName":"Howard Y. Chang","firstName":"Howard","href":"http://med.stanford.edu/profiles/Howard_Chang","researchInterest":"The Chang group is focused on two fundamental questions in epithelial biology: (1) the basis of positional identities in epidermal structures throughout the body, and (2) how those signals and boundaries may be abrogated to allow cancer metastasis. We are investigating the roles of site-specific fibroblast differentiation in patterning the epidermis, and dissecting the mechanisms of wound healing programs in cancer metastasis."},{"lastName":"Negrin","clinicalFocus":[{"focus":"Blood and Marrow Transplantation"},{"focus":"Hematology"}],"appointments":[{"appointment":"Professor,Medicine - Division: Blood and  \r\nMarrow Transplantation"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Medicine - Division: Blood and  \r\nMarrow Transplantation","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4138&type=small&showNoImage","displayName":"Robert Negrin","firstName":"Robert","href":"http://med.stanford.edu/profiles/Robert_Negrin","researchInterest":"Our labaratory focuses on the study of immune recognition by T and NK cells with special emphasis on graft vs host disease and graft vs tumor reactions. We utilize both murine and human systems in an effort to enhance graft vs tumor reactions while controlling graft vs host disease. We have developed bioluminescence models in collaboration with the Contag laboratory to study the trafficking of immune effector cells with a special emphasis on NK, T and regulatory T cells."},{"lastName":"Chen","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Assistant Professor,Microbiology & Immunology - Baxter Laboratory","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6384&type=small&showNoImage","displayName":"Chang-Zheng Chen","firstName":"Chang-Zheng","href":"http://med.stanford.edu/profiles/Chang-Zheng_Chen","researchInterest":"We study the genetic networks controlled by regulatory RNAs, such as microRNAs (miRNAs), and currently focus on two complementary aspects of miRNA biology: (1) The roles of miRNAs in modulating the development, function, and pathogenesis of vertebrate immune systems and (2) the mechanisms by which these regulatory RNAs control gene expression."},{"lastName":"Twist","clinicalFocus":[{"focus":"Hematology/Oncology/Stem Cell Transplant,  Pediatric"},{"focus":"Oncology (Cancer), Pediatric"},{"focus":"Pediatric Hematology-Oncology"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Pediatrics - Hematology/Oncology"}],"primaryAppointment":"Associate Professor - Med Center Line,Pediatrics - Hematology/Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4366&type=small&showNoImage","displayName":"Clare J. Twist","firstName":"Clare","href":"http://med.stanford.edu/profiles/Clare_Twist","researchInterest":"My primary research interest is in the study and treatment of neuroblastoma. My clinical interests also include Wilms tumor, hepatoblastoma, post-transplant lymphoproliferative disorders, phase I therapies for hematologic malignancies, as well as  palliative and end of life care."},{"lastName":"Rouse","clinicalFocus":[{"focus":"Pathology and Laboratory Medicine"},{"focus":"Anatomic/Clinical Pathology"}],"appointments":[{"appointment":"Professor - Med Center Line,Pathology"}],"primaryAppointment":"Professor - Med Center Line,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4491&type=small&showNoImage","displayName":"Robert V Rouse","firstName":"Robert","href":"http://med.stanford.edu/profiles/Robert_Rouse","researchInterest":"My recent research efforts are currently focused in the field of applications of immunohistology to the diagnosis of human neoplasms. This work is predominantly aimed at characterizing markers for the identification of non-lymphoid neoplasms and at establishing criteria for their evaluation in diagnostic situations."},{"lastName":"Venkatasubrahmanyam","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biomedical Informatics (IDP)"}],"primaryAppointment":"Postdoctoral Research fellow, Biomedical Informatics (IDP)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10102&type=small&showNoImage","displayName":"Shivkumar Venkatasubrahmanyam","firstName":"Shivkumar","href":"http://med.stanford.edu/profiles/Shivkumar_Venkatasubrahmanyam","researchInterest":""}]}