{"result":[{"lastName":"Sidow","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Pathology"},{"appointment":"Associate Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4393&type=small&showNoImage","displayName":"Arend Sidow","firstName":"Arend","href":"http://med.stanford.edu/profiles/Arend_Sidow","researchInterest":"We study the function and molecular evolution of proteins and noncoding functional elements in the genome.  Please refer to our web site for more information:  http://mendel.stanford.edu/SidowLab/index.html"},{"lastName":"Lorch","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Structural Biology"}],"primaryAppointment":"Associate Professor (Research),Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4116&type=small&showNoImage","displayName":"Yahli Lorch","firstName":"Yahli","href":"http://med.stanford.edu/profiles/Yahli_Lorch","researchInterest":""},{"lastName":"Fire","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Professor,Genetics"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3989&type=small&showNoImage","displayName":"Andrew Fire","firstName":"Andrew","href":"http://med.stanford.edu/profiles/Andrew_Fire","researchInterest":"We study natural cellular mechanisms for adapting to genetic change. These include systems activated during normal development and those for detecting and responding to foreign or unwanted genetic activity. Underlying these studies are questions of how a cells can distinguish information as \"self\" versus \"nonself\" or \"wanted\" versus \"unwanted\"."},{"lastName":"Velandy Chodaparambil","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Structural Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9946&type=small&showNoImage","displayName":"Jay Chodaparambil","firstName":"Jayanth","href":"http://med.stanford.edu/profiles/Jayanth_Velandy Chodaparambil","researchInterest":""},{"lastName":"Bell","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pathology"}],"primaryAppointment":"Postdoctoral Research fellow, Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=11479&type=small&showNoImage","displayName":"Oliver Bell","firstName":"Oliver","href":"http://med.stanford.edu/profiles/Oliver_Bell","researchInterest":""},{"lastName":"Lu","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Cancer/Stem Cell Biology Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Cancer/Stem Cell Biology Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8826&type=small&showNoImage","displayName":"Rong Lu","firstName":"Rong","href":"http://med.stanford.edu/profiles/Rong_Lu","researchInterest":""},{"lastName":"Villeneuve","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4035&type=small&showNoImage","displayName":"Anne Villeneuve","firstName":"Anne","href":"http://med.stanford.edu/profiles/Anne_Villeneuve","researchInterest":"Mechanisms underlying homologous chromosome pairing, DNA recombination and chromosome remodeling during meiosis, using the nematode Caenorhabditis elegans as an experimental system.  High-resolution 3-D imaging of dynamic reorganization of chromosome architecture.  Role of protease inhibitors in regulating sperm activation."},{"lastName":"Shih","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Health Research & Policy - Biostatistics"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Assistant Professor,Health Research & Policy - Biostatistics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7951&type=small&showNoImage","displayName":"Mei-Chiung Shih","firstName":"Mei-Chiung","href":"http://med.stanford.edu/profiles/Mei-Chiung_Shih","researchInterest":""},{"lastName":"Wong","clinicalFocus":[],"appointments":[{"appointment":"Professor,Statistics"},{"appointment":"Professor (By courtesy),Biology (School of Humanities and Sciences)"},{"appointment":"Professor,Health Research & Policy - Biostatistics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Statistics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6454&type=small&showNoImage","displayName":"Wing Wong","firstName":"Wing","href":"http://med.stanford.edu/profiles/Wing_Wong","researchInterest":"Current interest centers on the application of statistics to problems arsing from biology. We are particularly interested in questions concerning gene regulation and signal transduction."},{"lastName":"Petrov","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6234&type=small&showNoImage","displayName":"Dmitri Petrov","firstName":"Dmitri","href":"http://med.stanford.edu/profiles/Dmitri_Petrov","researchInterest":""},{"lastName":"Carroll","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biochemistry"}],"primaryAppointment":"Postdoctoral Research fellow, Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9403&type=small&showNoImage","displayName":"Christopher Carroll","firstName":"Christopher","href":"http://med.stanford.edu/profiles/Christopher_Carroll","researchInterest":""},{"lastName":"Tan","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Genetics"},{"appointment":"Assistant Professor,Microbiology & Immunology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3853&type=small&showNoImage","displayName":"Man-Wah Tan","firstName":"Man-Wah","href":"http://med.stanford.edu/profiles/Man-Wah_Tan","researchInterest":"Genome-wide analysis of host-pathogen interactions using a bacteria-C. elegans pathogenesis model; molecular mechanisms of virulence of bacterial pathogens; regulation of host-pathogen interactions by fatty acids and the nervous system; elucidate the distinctions in the regulation of immunity, stress and longevity."},{"lastName":"Liu","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9664&type=small&showNoImage","displayName":"Chih Long Liu","firstName":"Chih","href":"http://med.stanford.edu/profiles/Chih_Liu","researchInterest":""},{"lastName":"Shahram","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Statistics"}],"primaryAppointment":"Postdoctoral Research fellow, Statistics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8678&type=small&showNoImage","displayName":"Morteza Shahram","firstName":"Morteza","href":"http://med.stanford.edu/profiles/Morteza_Shahram","researchInterest":""},{"lastName":"Altman","clinicalFocus":[],"appointments":[{"appointment":"Professor,Bioengineering"},{"appointment":"Professor,Medicine - BMIR"},{"appointment":"Professor (By courtesy),Computer Science"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4706&type=small&showNoImage","displayName":"Russ B. Altman","firstName":"Russ","href":"http://med.stanford.edu/profiles/Russ_Altman","researchInterest":"I refer you to my web page for detailed list of interests, projects and publications.  In addition to pressing the link here, you can search \"Russ Altman\" on http://www.google.com/"},{"lastName":"Butte","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Pediatrics - Cancer Biology"},{"appointment":"Assistant Professor,Medicine"},{"appointment":"Assistant Professor (By courtesy),Computer Science"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Assistant Professor,Pediatrics - Cancer Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6603&type=small&showNoImage","displayName":"Atul Butte","firstName":"Atul","href":"http://med.stanford.edu/profiles/Atul_Butte","researchInterest":"Translational bioinformatics has been defined as the development of analytic\r\nmethods to help transform increasingly voluminous genomic and biological data into diagnostics and therapeutics for the clinician.  The long-term research goal of the Butte Lab is to develop translational bioinformatics methods to reason over many available genome-scale measurement and experimental modalities, and apply these methods to study complex disorders in genomic medicine, especially obesity and diabetes."},{"lastName":"Jiang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Statistics"}],"primaryAppointment":"Postdoctoral Research fellow, Statistics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=14794&type=small&showNoImage","displayName":"Hui Jiang","firstName":"Hui","href":"http://med.stanford.edu/profiles/Hui_Jiang","researchInterest":""},{"lastName":"Clark","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurobiology"}],"primaryAppointment":"Postdoctoral Research fellow, Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8632&type=small&showNoImage","displayName":"Damon Clark","firstName":"Damon","href":"http://med.stanford.edu/profiles/Damon_Clark","researchInterest":""},{"lastName":"Francke","clinicalFocus":[{"focus":"Clinical Genetics"},{"focus":"Neurogenetics"}],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Professor,Pediatrics"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4281&type=small&showNoImage","displayName":"Uta Francke","firstName":"Uta","href":"http://med.stanford.edu/profiles/Uta_Francke","researchInterest":"Functional consequences and pathogenetic mechanisms of mutations and microdeletions in human neurogenetic syndromes and mouse models: Williams-Beuren syndrome, a heterozygous 1.6 megabase deletion; Rett syndrome, caused by mutations in the X-linked methyl-CpG binding protein 2 (MECP2) gene. Mechanisms of genomic imprinting: Prader Willi syndrome"},{"lastName":"Hershberg","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10299&type=small&showNoImage","displayName":"Ruth Hershberg","firstName":"Ruth","href":"http://med.stanford.edu/profiles/Ruth_Hershberg","researchInterest":"The aim of my research is to investigate the mechanisms, frequency, and consequences of the evolutionary shifts experienced by bacteria. Some more specific areas of research include:\r\n\r\n(1)  Quantifying shifts in the strength of purifying selection and understanding the consequences of such shifts\r\n \r\n(2)  Determining whether shifts in nucleotide content are driven by shifts in mutation or shifts in selection\r\n\r\n(3)  Establishing the mechanisms of shifts in codon usage bias"},{"lastName":"Qiu","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Radiology"}],"primaryAppointment":"Postdoctoral Research fellow, Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10272&type=small&showNoImage","displayName":"Peng Qiu","firstName":"Peng","href":"http://med.stanford.edu/profiles/Peng_Qiu","researchInterest":""},{"lastName":"Covert","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Bioengineering"},{"appointment":"Assistant Professor (By courtesy),Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7986&type=small&showNoImage","displayName":"Markus Covert","firstName":"Markus","href":"http://med.stanford.edu/profiles/Markus_Covert","researchInterest":"Our focus is on building computational models of complex biological processes, and using them to guide an experimental program. Such an approach leads to a relatively rapid identification and validation of previously unknown components and interactions. Biological systems of interest include metabolic, regulatory and signaling networks as well as cell-cell interactions. Current research involves the dynamic behavior of NF-kappaB, an important family of transcription factors."},{"lastName":"Gordon","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9070&type=small&showNoImage","displayName":"Matthew Gordon","firstName":"Matthew","href":"http://med.stanford.edu/profiles/Matthew_Gordon","researchInterest":""},{"lastName":"Woo","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Dermatology"}],"primaryAppointment":"Postdoctoral Research fellow, Dermatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9651&type=small&showNoImage","displayName":"Wei-Meng Woo","firstName":"Wei","href":"http://med.stanford.edu/profiles/Wei_Woo","researchInterest":""},{"lastName":"Davis","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4117&type=small&showNoImage","displayName":"Ronald Davis","firstName":"Ronald","href":"http://med.stanford.edu/profiles/Ronald_Davis","researchInterest":"We are using Saccharomyces cerevisiae and Human to conduct whole genome analysis projects. The yeast genome sequence has approximately 6,000 genes. We have made a set of haploid and diploid strains (21,000) containing a complete deletion of each gene. In order to facilitate whole genome analysis each deletion is molecularly tagged with a unique 20-mer DNA sequence. This sequence acts as a molecular bar code and makes it easy to identify the presence of each deletion."}]}