Adolf Pfefferbaum
Publication Details
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In vivo detection and functional correlates of white matter microstructural disruption in chronic alcoholism.
Alcohol Clin Exp Res. 2000; (8): 1214-21
Postmortem studies report degradation of brain white matter microstructure in chronic alcoholism, but until recently, in vivo neuroimaging could provide measurement only at a macrostructural level. The development of magnetic resonance diffusion tensor imaging (DTI) for clinical use offers a method for depicting and quantifying the diffusion properties of white matter expressed as intravoxel and intervoxel coherence of tracts and fibers.
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