Alan F. Schatzberg
Publication Details
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The efficacy of divalproex sodium in the treatment of agitation associated with major depression.
J Clin Psychopharmacol. 2005; (5): 476-9
Agitation is both a feature of major depression and a common side effect of antidepressant treatment. Depressive agitation correlates with overall severity of illness and suicide risk, whereas treatment-emergent agitation may contribute to early discontinuation of pharmacotherapy. Thus, agitation merits investigation as a treatment target in clinical depression.
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