Community Academic Profiles

Manisha Desai

Publication Details

  • A concentrated aglycone isoflavone preparation (GCP) that demonstrates potent anti-prostate cancer activity in vitro and in vivo.

    Bemis DL, Capodice JL, Desai M, Buttyan R, Katz AE. Clin Cancer Res. 2004; 10 (15): 5282-92

    Isoflavones have anticancer activities, but naturally occurring isoflavones are predominantly glycosylated and poorly absorbed. Genistein combined polysaccharide (GCP; Amino Up Chemical Co., Sapporo, Japan), is a fermentation product of soy extract and basidiomycetes mycillae that is enriched in biologically active aglycone isoflavones. This study analyzes GCP in vitro and in vivo for potential utility as a prostate cancer chemopreventative agent.

    PubMedID: 15297432

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