Eric Kool
Publication Details
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The components of xRNA: synthesis and fluorescence of a full genetic set of size-expanded ribonucleosides.
Org Lett. 2011; (4): 676-9
The synthesis and properties of a full set of four benzo-expanded ribonucleosides (xRNA), analogous to A, G, C, and U RNA monomers, are described. The nucleosides are efficient fluorophores with emission maxima of 369-411 nm. The compounds are expected to be useful as RNA pathway probes and as components of an unnatural ribopolymer.
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