Sanjiv Sam Gambhir, MD, PhD
Publication Details
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A quantitative physiologic model of blood oxygenation for functional magnetic resonance imaging.
Invest Radiol. 1995; (11): 669-82
Variations in venous deoxyhemoglobin levels in response to neuronal activation represent a complex interplay between focal changes in cerebral blood flow (CBF), cerebral blood volume (CBV), and regional metabolism. The authors present a mathematic model that characterizes the response of venous oxygenation to changes in these variables.
