John M. Pauly
Publication Details
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Prediction of glycosaminoglycan content in human cartilage by age, T1ρ and T2 MRI.
Osteoarthritis Cartilage. 2011; (2): 171-9
A relationship between T1ρ relaxation time and glycosaminoglycan (GAG) content has been demonstrated in chemically degraded bovine cartilage, but has not been demonstrated with quantitative biochemistry in human cartilage. A relationship has also been established between T2 relaxation time in cartilage and osteoarthritis (OA) severity. We hypothesized that T1ρ relaxation time would be associated with GAG content in human cartilage with normal T2 relaxation times.
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