Community Academic Profiles

Brian Kobilka

Publication Details

  • Tandem facial amphiphiles for membrane protein stabilization.

    Chae PS, Gotfryd K, Pacyna J, Miercke LJ, Rasmussen SG, Robbins RA, Rana RR, Loland CJ, Kobilka B, Stroud R, Byrne B, Gether U, Gellman SH. J Am Chem Soc. 2010; 132 (47): 16750-2

    We describe a new type of synthetic amphiphile that is intended to support biochemical characterization of intrinsic membrane proteins. Members of this new family displayed favorable behavior with four of five membrane proteins tested, and these amphiphiles formed relatively small micelles.

    PubMedID: 21049926

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