Alan M. Krensky, M.D.
Publication Details
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Granulysin: a novel host defense molecule.
Am J Transplant. 2005; (8): 1789-92
Granulysin is a novel cationic molecule present in the granules of cytotoxic T lymphocytes and natural killer cells. Cytotoxic T lymphocytes have long been associated with graft destruction in transplant rejection. Recent studies implicate granulysin in cell-mediated cytotoxicity, chemoattraction, immune activation and as a potential diagnostic biomarker for transplant rejection.
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