John Ioannidis
Publication Details
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Polymorphisms in the 5' flank of COL1A1 gene and osteoporosis: meta-analysis of published studies.
Osteoporos Int. 2011; (3): 911-21
A meta-analysis of studies was conducted involving 24,511 participants with 7,864 fractures in which polymorphisms in the 5' flank of COL1A1 (rs1107946, rs2412298, and rs1800012) were related to osteoporosis phenotypes. Polymorphisms of all three sites were associated with BMD, and rs1800012 was associated with fracture but effect sizes were modest.
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