Mark A. Kay, M.D., Ph.D.
Publication Details
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Donor-derived, liver-specific protein expression after bone marrow transplantation.
Transplantation. 2004; (4): 530-6
Bone marrow transplantation (BMT) may represent a novel mechanism to deliver a functional gene to a deficient liver. Bone marrow-derived hepatocytes are rare and without a defined contribution to liver function. Consequently, the clinical significance of BMT to treat liver disease is unclear. We sought to quantify bone marrow-derived hepatocyte protein expression after BMT and determine whether the process is inducible with liver injury.
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