Renee A. Reijo Pera, Ph.D.
Publication Details
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Severe oligozoospermia resulting from deletions of azoospermia factor gene on Y chromosome.
Lancet. 1996; (9011): 1290-3
About 13% of cases of non-obstructive azoospermia are caused by deletion of the azoospermia factor (AZF), a gene or gene complex normally located on the long arm of the Y chromosome. Oligozoospermia is far more common than azoospermia, but little is known about genetic causes. We investigated whether severe oligozoospermia is caused by AZF deletions and, if so, whether those deletions are present in mature spermatozoa.
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