Steven M. Block
Publication Details
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Estimating the persistence length of a worm-like chain molecule from force-extension measurements.
Biophys J. 1999; (1 Pt 1): 409-13
We describe a simple computation of the worm-like chain model and obtain the corresponding force-versus-extension curve. We propose an improvement to the Marko and Siggia interpolation formula of Bustamante et al (Science 1994, 265:1599-1600) that is useful for fitting experimental data. We apply it to the experimental elasticity curve of single DNA molecules. Finally, we present a tool to study the agreement between the worm-like chain model and experiments.
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