Daniel A. Arber, M.D.
Publication Details
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Aneuploidy in benign seminal vesicle epithelium: an example of the paradox of ploidy studies.
Mod Pathol. 1991; (6): 687-9
To evaluate if the nuclear enlargement and irregularity of non-neoplastic seminal vesicle epithelium were associated with an abnormal DNA content, 30 seminal vesicles obtained from radical prostatectomies were analyzed by flow cytometry. Twenty-eight (93.3%) of the seminal vesicles showed characteristic diploid histograms, while two (6.7%) showed histograms characteristic of aneuploidy. These results are discussed and other reported examples of aneuploidy in nonmalignant tissues are reviewed.
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