Community Academic Profiles–

James L. Zehnder, M.D.

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Publication Details

  • Variability of polymerase chain reaction detection of the bcl-2-IgH translocation in an international multicentre study.

    Johnson PW, Swinbank K, MacLennan S, Colomer D, Debuire B, Diss T, Gabert J, Gupta RK, Haynes A, Kneba M, Lee MS, Macintyre E, Mensink E, Moos M, Morgan GJ, Neri A, Johnson A, Reato G, Salles G, van't Veer MB, Zehnder JL, Zucca E, Selby PJ, Cotter FE. Ann Oncol. 1999; 10 (11): 1349-54

    The capacity of the polymerase chain reaction (PCR) to detect very low numbers of cells bearing a t(14;18) translocation has led to its application in assessment of the results of treatment for follicular lymphoma, and suggestions that therapy might be guided by molecular studies. To test the reliability of PCR a collaborative study was undertaken to compare results from different laboratories in Europe and North America.

    PubMedID: 10631464

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