Hunter Fraser
Publication Details
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Evolutionary rate depends on number of protein-protein interactions independently of gene expression level.
BMC Evol Biol. 2004: 13
Whether or not a protein's number of physical interactions with other proteins plays a role in determining its rate of evolution has been a contentious issue. A recent analysis suggested that the observed correlation between number of interactions and evolutionary rate may be due to experimental biases in high-throughput protein interaction data sets.
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