Alice S Whittemore
Publication Details
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Family data determine all parameters in Mendelian incomplete penetrance models.
Ann Hum Genet. 1991; (Pt 2): 175-7
We show that data on the frequency of occurrence of an hereditary trait in family members can be used to determine all four parameters in a Mendelian genetic model with incomplete penetrance. Thus previous statements in the literature that such data can determine only three combinations of the parameters are incorrect.
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