Lawrence Tim Goodnough
Publication Details
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Response of kaolin ACT to heparin: evaluation with an automated assay and higher heparin doses.
Ann Thorac Surg. 1996; (3): 795-9
Because previous reports suggest that the linear relationship between celite activated clotting time (ACT) values and heparin sodium is disrupted if values exceed 500 to 600 seconds, this study was designed to evaluate the relationship of kaolin activated clotting time (ACT) values to high in vitro heparin concentrations. In addition, the relationship of kaolin ACT to heparin concentration as determined manually was compared with that obtained with an automated heparin dose response assay.
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