Hendrikus Lemmens
Publication Details
-
Pharmacokinetic-pharmacodynamic modeling in drug development: application to the investigational opioid trefentanil.
Clin Pharmacol Ther. 1994; (3): 261-71
We determined the possible benefits of a new opioid, trefentanil, relative to fentanyl and alfentanil using high-resolution pharmacokinetic-pharmacodynamic modeling and computer simulations of clinical dosing scenarios.
Help