James Spudich
Publication Details
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Myosin structure/function: a combined mutagenesis-crystallography approach.
Curr Opin Struct Biol. 1995; (2): 181-6
In the past year, the structure of the regulatory domain of scallop myosin has joined that of the chicken skeletal muscle myosin subfragment 1 and provided insights into the regulation of myosin function. Mutagenesis studies in a variety of systems have used the information provided by these structures to create mutant myosins to test models of chemomechanical transduction and its regulation.
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