Edward Riley
Publication Details
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Lumbar epidural morphine in humans and supraspinal analgesia to experimental heat pain.
Anesthesiology. 2000; (2): 312-24
Epidural administration of morphine is a common analgesic technique to manage pain. Morphine spreads from the epidural space to the cerebrospinal fluid and then rostrally, causing side effects mediated by the brain stem. However, data on the rostral spread of morphine-mediated analgesia are sparse. This study examined the rostral spread of analgesic effects on heat and electrical pain after epidural administration of morphine.
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