Eric Sibley, M.D., Ph.D.
Publication Details
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The homeodomain protein Cdx2 regulates lactase gene promoter activity during enterocyte differentiation.
Gastroenterology. 2000; (1): 115-27
Lactase is the intestinal disaccharidase responsible for digestion of lactose, the predominant carbohydrate in milk. Transcription of the lactase gene is activated during enterocyte differentiation. We have characterized the interaction between the lactase promoter and Cdx2, a homeodomain protein involved in regulating intestinal development and differentiation.
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