Philip S. Tsao, PhD
Publication Details
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Enhanced endothelial adhesiveness in hypercholesterolemia is attenuated by L-arginine.
Circulation. 1994; (5): 2176-82
We have shown that chronic administration of the nitric oxide (NO) precursor L-arginine normalizes NO-dependent vasodilation and markedly inhibits atherogenesis in a hypercholesterolemic rabbit model. We hypothesized that this antiatherogenic effect is due to modulation of endothelial adhesiveness by endothelium-derived NO.
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