Laura Attardi
Publication Details
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SKP-ing TAp63: stem cell depletion, senescence, and premature aging.
Cell Stem Cell. 2009; (1): 1-2
The p53 family member p63 comprises multiple isoforms and is critical for stratified epithelial development. In this issue of Cell Stem Cell, by generating isoform-specific knockout mice, Su et al. (2009) reveal pivotal roles for TAp63 in the maintenance of dermal and epidermal precursors, genomic stability, and organismal longevity.
