C. Garrison Fathman
Publication Details
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Ternary complex therapy for autoimmune disease.
Hosp Pract (1995). 1995; (8): 57-8, 60-2, 64-5
Induction of an immune response is remarkably simple, involving the interaction of three components: processed antigen, an MHC class II molecule, and a CD4 T-cell receptor. Each part of this ternary complex represents a novel target for interventions that may block subsequent effector phenomena of autoimmune disease. Such specific treatments will be less toxic than those currently available.
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