Sheri Krams
Publication Details
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Effect of cyclosporine and tacrolimus on the growth of Epstein-Barr virus-transformed B-cell lines.
Transplantation. 1998; (9): 1248-55
Transplant patients receiving immunosuppressive drugs are at increased risk for Epstein-Barr virus (EBV)-associated disorders including posttransplant lymphoproliferative disorder. The function of T lymphocytes, which are critical to preventing the expansion of EBV-infected B cells, is inhibited by immunosuppressive drugs. The purpose of this study was to determine whether immunosuppressive drugs have direct effects on EBV-infected B cells.
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