Daria Mochly-Rosen
Publication Details
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Preserved coronary endothelial function by inhibition of delta protein kinase C in a porcine acute myocardial infarction model.
Int J Cardiol. 2009; (2): 256-9
Previous studies demonstrate impairment of endothelial-dependent vasodilation after ischemia/reperfusion (I/R). Though we have demonstrated that inhibition of delta protein kinase C (delta PKC) at reperfusion reduces myocyte damage and improves cardiac function in a porcine acute myocardial infarction (AMI) model, impact of the selective delta PKC inhibitor on epicardial coronary endothelial function remains unknown.
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