Carlos Milla
Publication Details
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Long-term effects of aerosolised rhDNase on pulmonary disease progression in patients with cystic fibrosis.
Thorax. 1998; (12): 1014-7
After multiple studies, including clinical trials, suggested some mild clinical benefits from the use of rhDNase by patients with cystic fibrosis, a widespread acceptance of the drug has followed. However, long-term effects, specifically on lung disease progression, have not been demonstrated. Experience with the use of this drug in a single cystic fibrosis centre is presented and compared with the trends seen in the patient population of the centre before the introduction of the drug.
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