Roeland Nusse
Publication Details
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Mutants in the mouse NuRD/Mi2 component P66alpha are embryonic lethal.
PLoS One. 2007; (6): e519
The NuRD/Mi2 chromatin complex is involved in histone modifications and contains a large number of subunits, including the p66 protein. There are two mouse and human p66 paralogs, p66alpha and p66beta. The functions of these genes are not clear, in part because there are no mutants available, except in invertebrate model systems.
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