Community Academic Profiles

David Liang, MD, PhD

Publication Details

  • Tenting volume: three-dimensional assessment of geometric perturbations in functional mitral regurgitation and implications for surgical repair.

    Tibayan FA, Wilson A, Lai DT, Timek TA, Dagum P, Rodriguez F, Zasio MK, Liang D, Daughters GT, Ingels NB, Miller DC. J Heart Valve Dis. 2007; 16 (1): 1-7

    Functional mitral regurgitation (FMR) often complicates dilated cardiomyopathy (DCM), and portends a poor prognosis. Debate over the optimal treatment continues, underscoring the present incomplete understanding of the patho-anatomic mechanisms of this disease. Studies of mitral tenting volume and tenting area, and echocardiographic measures of abnormal apical systolic leaflet geometry have linked mitral leaflet deformation with subvalvular left ventricular (LV) remodeling in chronic ischemic MR. The relative contributions of annular versus subvalvular remodeling in FMR due to DCM are less clear. Here, the validity of 3-D measurement of mitral deformation, tenting volume, as a correlate of MR in DCM, was tested. The ability of annular and subvalvular remodeling to predict mitral deformation was then determined.

    PubMedID: 17315376

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