Frederick T. Chin, Ph.D.
Publication Details
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No-carrier-added [18F]fluoroarenes from the radiofluorination of diaryl sulfoxides.
ChemCommun. 2013
No-carrier-added [18F]fluoroarenes were synthesized thorough the radiofluorination of diaryl sulfoxides with [18F]fluoride ion. Diaryl sulfoxides bearing a para electron-withdrawing substituent readily gave the corresponding 4 [18F]fluoroarenes in high tadiochemical yields. This process broadens the scope for preparing novel 18F-labeling synthons and PET radiotracers.
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