Holden Maecker
Publication Details
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The phenotypic distribution and functional profile of tuberculin-specific CD4 T-cells characterizes different stages of TB infection.
Cytometry B Clin Cytom. 2012; (6): 360-8
Recent publications have suggested that altered proportions of functional CD4 T-cell subsets correlate with active pulmonary TB. Also, CD27-expression on tuberculin-activated IFN-γ(+) CD4 T-cells is known to differ significantly between patients with active pulmonary TB and healthy TB-unexposed BCG vaccinees. Here, we explore links between CD4 T-cell phenotype, multiple functional subsets, and control of TB.
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