Roger Kornberg
Publication Details
-
A bridge to transcription by RNA polymerase.
J Biol. 2008; (10): 39ABSTRACT: A comprehensive survey of single amino-acid substitution mutations critical for RNA polymerase function published in Journal of Biology supports a proposed mechanism for polymerase action in which movement of the polymerase 'bridge helix' promotes transcriptional activity in cooperation with a critical substrate-interaction domain, the 'trigger loop'.
Help