John Ioannidis
Publication Details
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Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.
Lancet. 2012; (9844): 815-23
Osteoarthritis is the most common form of arthritis worldwide and is a major cause of pain and disability in elderly people. The health economic burden of osteoarthritis is increasing commensurate with obesity prevalence and longevity. Osteoarthritis has a strong genetic component but the success of previous genetic studies has been restricted due to insufficient sample sizes and phenotype heterogeneity.
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