Community Academic Profiles

Rachel Manber

Publication Details

  • Therapeutic alliance in depression treatment: controlling for prior change and patient characteristics.

    Klein DN, Schwartz JE, Santiago NJ, Vivian D, Vocisano C, Castonguay LG, Arnow B, Blalock JA, Manber R, Markowitz JC, Riso LP, Rothbaum B, McCullough JP, Thase ME, Borian FE, Miller IW, Keller MB. J Consult Clin Psychol. 2003; 71 (6): 997-1006

    Although many studies report that the therapeutic alliance predicts psychotherapy outcome, few exclude the possibility that this association is accounted for by 3rd variables, such as prior improvement and prognostically relevant patient characteristics. The authors treated 367 chronically depressed patients with the cognitive-behavioral analysis system of psychotherapy (CBASP), alone or with medication. Using mixed effects growth-curve analyses, they found the early alliance significantly predicted subsequent improvement in depressive symptoms after controlling for prior improvement and 8 prognostically relevant patient characteristics. In contrast, neither early level nor change in symptoms predicted the subsequent level or course of the alliance. Patients receiving combination treatment reported stronger alliances with their psychotherapists than patients receiving CBASP alone. However, the impact of the alliance on outcome was similar for both treatment conditions.

    PubMedID: 14622075

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