Gregory W. Albers
Publication Details
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Aptiganel hydrochloride in acute ischemic stroke: a randomized controlled trial.
JAMA. 2001; (21): 2673-82
Tissue plasminogen activator is the only thrombolytic agent approved in the United States for treatment of acute ischemic stroke, and has limitations. Aptiganel hydrochloride is a novel and selective ligand for the ion-channel site of the N-methyl-D-aspartate receptor-channel complex and a promising neuroprotective agent in animal models of focal brain ischemia.
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