Emmanuel Mignot
Publication Details
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Absence of ubiquitinated inclusions in hypocretin neurons of patients with narcolepsy.
Neurology. 2009; (7): 511-7
The cause of hypocretin cell loss in human narcolepsy-cataplexy is unknown but has been suggested to be neurodegenerative in nature. To test this hypothesis, we evaluated the remaining hypocretin cells in human narcolepsy brains for the presence of aggregated protein inclusions, gliosis, and inflammation.
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