Peter H. Hwang
Publication Details
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Inhibition of inflammatory mediators: role of statins in airway inflammation.
Otolaryngol Head Neck Surg. 2011; (6): 982-7
To determine if statins induce anti-inflammatory effects in upper airway inflammation. Mediators of innate and adaptive immunity regulate airway inflammation. Release of these mediators involves enzymatic conversion of polyunsaturated fatty acids into biologically active mediators, which can be blocked by statins. Although upper airway inflammation and chronic sinusitis occur in millions of patients with asthma worldwide, the anti-inflammatory effects of statins in upper airway inflammation have not been previously studied.
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