Paul Utz
Publication Details
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Modulation of peripheral B cell tolerance by CD72 in a murine model.
Arthritis Rheum. 2008; (10): 3192-204
B cells play a dominant role in the pathogenesis of several autoimmune diseases, including systemic lupus erythematosus. It is not well understood how B cell signaling contributes to autoantibody production. The goal of this study was to elucidate the role of CD72 in modulating B cell receptor (BCR)-mediated tolerogenic signaling and peripheral B cell tolerance.
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