Community Academic Profiles

Zhen Cheng

Publication Details

  • Optical imaging with her2-targeted affibody molecules can monitor hsp90 treatment response in a breast cancer xenograft mouse model.

    van de Ven SM, Elias SG, Chan CT, Miao Z, Cheng Z, De A, Gambhir SS. Clin Cancer Res. 2012; 18 (4): 1073-81

    To determine whether optical imaging can be used for in vivo therapy response monitoring as an alternative to radionuclide techniques. For this, we evaluated the known Her2 response to 17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride (17-DMAG) treatment, an Hsp90 inhibitor.

    PubMedID: 22235098

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