Community Academic Profiles

John Cooke, MD, PhD

Publication Details

  • A central role for nicotinic cholinergic regulation of growth factor-induced endothelial cell migration.

    Ng MK, Wu J, Chang E, Wang BY, Katzenberg-Clark R, Ishii-Watabe A, Cooke JP. Arterioscler Thromb Vasc Biol. 2007; 27 (1): 106-12

    An endothelial nicotinic acetylcholine receptor (nAChR) participates in atherogenesis and tumorigenesis by promoting neovascularization. To date, the mechanisms of nAChR-mediated angiogenesis and their relationship to angiogenic factors, eg, VEGF and bFGF, are unknown.

    PubMedID: 17082486

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