James F. Fries
Publication Details
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Response to therapy in rheumatoid arthritis is influenced by immediately prior therapy.
J Rheumatol. 1997; (5): 838-44
Clinicians do not often employ washout periods before prescribing a change in therapy for rheumatoid arthritis (RA). As a result, the observed effectiveness or lack of effectiveness of a new drug actually represents the effectiveness of that drug had the patient been taking placebo minus the residual effectiveness of the old drug.
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